[Toxicological evaluation of ethyl acetate in conditions of sealed cabin atmospheres].

Ethyl acetate was studied as an atmosphere contaminant in an enclosed environment. A 90-day continuous experiment on 160 white rats and 120 white mice with three concentrations of the compound (43, 10 and 2 mg/m3) was carried out. Ethyl acetate used in the first two concentrations caused functional disturbances in the state of animals and morphological changes in their viscera. Ethyl acetate at a concentration of 2 mg/m3 was ineffective. The data obtained allow recommendations of permissible concentrations of ethyl acetate vapours in an enclosed atmosphere in relation to a different time of man's exposure.