刺天茄种子对附睾尾精子氧化电位的影响。
Effect of Solanum surattense seed on the oxidative potential of cauda epididymal spermatozoa.
作者信息
Thirumalai T, David E, Viviyan Therasa S, Elumalai E K
机构信息
Post Graduate and Research Department of Zoology, Voorhees College, Physiology Wing, Vellore-632 001, Tamilnadu, India.
出版信息
Asian Pac J Trop Biomed. 2012 Jan;2(1):21-3. doi: 10.1016/S2221-1691(11)60183-4.
OBJECTIVE
To evaluate the effect of aqueous seed extract of Solanum surattense (S. surattense) on the oxidative potential of cauda epididymal spermatozoa.
METHODS
S. surattense seed extract was orally administered at the dosage of 10 mg/kg b.w. for 15 days, after which aspartate transferase (AST), alanine transferase (ALT), glutamate dehydrogenase (GDH), citric acid and iso-citrate dehydrogenase (ICDH) were assayed.
RESULTS
The activity levels of the enzymes AST and ALT, which are considered to be the androgenicity in the sperm suspension, were depleted in the extract fed rats. The activity level of the enzyme ICDH, was reduced significantly in the treated group (P<0.001).
CONCLUSIONS
It can be concluded that the oral administration of the aqueous seed extract of S. surattense can deplete the oxidative stress of cauda epididymal spermatozoa in albino rats.
目的
评估刺天茄种子水提取物对附睾尾部精子氧化潜能的影响。
方法
以10 mg/kg体重的剂量口服给予刺天茄种子提取物，持续15天，之后测定天冬氨酸转氨酶（AST）、丙氨酸转氨酶（ALT）、谷氨酸脱氢酶（GDH）、柠檬酸和异柠檬酸脱氢酶（ICDH）。
结果
在喂食提取物的大鼠中，精子悬液中被认为具有雄激素性的AST和ALT酶的活性水平降低。治疗组中ICDH酶的活性水平显著降低（P<0.001）。
结论
可以得出结论，口服刺天茄种子水提取物可降低白化病大鼠附睾尾部精子的氧化应激。
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