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少见的非创伤性肠穿孔:一项回顾性研究的诊断与处理

Less common nontraumatic bowel perforations: diagnosis and management through a retrospective study.

作者信息

Gourgiotis Stavros, Liakos Nikolaos, Gemenetzis George, Seretis Charalampos, Aloizos Stavros, Vougas Vasilis, Drakopoulos Spyros

机构信息

Second Surgical Department, 401 General Army Hospital of Athens, Athens, Greece.

出版信息

Am Surg. 2013 Apr;79(4):381-7.

Abstract

Nontraumatic bowel perforation has always been a consideration because of associated morbidity and mortality. The aim of this study is to define etiologies, treatment, and outcomes as well as to highlight difficulties in the diagnosis and management of nontraumatic bowel perforation. We conducted a retrospective study of 35 patients with less common nontraumatic bowel perforations hospitalized during a six-year period. The most common cause was ulcerative colitis (34.3%). Abdominal pain was the constant symptom. Physical examination showed signs of peritoneal irritation in 29 cases. The abdominal radiograph failed to reveal abnormal findings in two patients; the abdominal computed tomography scan confirmed the diagnosis in all cases. Twenty patients (57.1%) were operated on within 24 hours of developing perforation, whereas seven patients (20%) were initially misdiagnosed. Most of the perforations were located only in the large intestine (60%). There was only one perforation in 25 patients (71.5%) and two or more perforations in 10 patients (28.5%). Many less common diseases are responsible for the spontaneous perforation of the bowel. Early diagnosis before the patient's general condition deteriorates decreases mortality and morbidity rates. Adequate resuscitation and emergency laparotomy followed by resection with or without anastomosis remains the treatment of choice.

摘要

由于相关的发病率和死亡率,非创伤性肠穿孔一直是需要考虑的问题。本研究的目的是明确病因、治疗方法和结果,并强调非创伤性肠穿孔诊断和管理中的难点。我们对6年内住院的35例少见的非创伤性肠穿孔患者进行了回顾性研究。最常见的病因是溃疡性结肠炎(34.3%)。腹痛是持续症状。体格检查显示29例有腹膜刺激征。2例患者腹部X线片未发现异常;所有病例腹部计算机断层扫描均确诊。20例患者(57.1%)在穿孔后24小时内接受手术,而7例患者(20%)最初被误诊。大多数穿孔仅位于大肠(60%)。25例患者(71.5%)仅有一处穿孔,10例患者(28.5%)有两处或更多处穿孔。许多少见疾病可导致肠道自发性穿孔。在患者全身状况恶化前早期诊断可降低死亡率和发病率。充分复苏和急诊剖腹手术,随后进行切除并酌情行吻合术仍是首选治疗方法。

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