Huttunen R, Kairaluoma M I, Mokka R E, Larmi T K
Surgery. 1977 Feb;81(2):184-8.
The etiology of nontraumatic small bowel perforations in 24 operated patients was as follows: strangulation in five, diverticulum in four, foreign bodies in four, idiopathic in three, Crogn's disease in two, malignant atrophic papulosis of Degos (MAP) in two, and tuberculosis, carcinoid tumor, radiotherapy, and iatrogenic in one. The high mortality rate in these patients appeared to be a funciton of the disease process rather than of the means of treatment. In favorable circumstances, as in strictly localized lesions with well known etiology and otherwise normal bowel, a simple closure of perforation is warranted. In more far advanced cases operated upon early enough, we still consider bowel resection and primary anastomosis as the best method of treatment, though it yielded poor results in procedures are advisable to protect the anastomosis.
24例接受手术治疗的非创伤性小肠穿孔患者的病因如下:绞窄性5例,憩室4例,异物4例,特发性3例,克罗恩病2例,德戈斯恶性萎缩性丘疹病(MAP)2例,结核、类癌肿瘤、放疗及医源性各1例。这些患者的高死亡率似乎是疾病进程的作用,而非治疗方式的结果。在有利的情况下,如病因明确且肠道其他部位正常的局限性病变,简单缝合穿孔是可行的。在足够早期进行手术的更晚期病例中,我们仍认为肠切除及一期吻合是最佳治疗方法,尽管在某些手术中效果不佳,但保护吻合口的操作是可取的。