Pauly S, Schulze F P, Horstmann O, Becker H, Grade M, Ghadimi M
Centrum für Muskuloskeletale Chirurgie, Charité Universitätsmedizin Berlin, Deutschland.
Zentralbl Chir. 2013 Jun;138(3):289-94. doi: 10.1055/s-0032-1328006. Epub 2013 Apr 10.
Despite modern surgical and intensive-care concepts, diffuse peritonitis remains a major source of high morbidity and mortality. The aim of this study was to critically evaluate the value of relaparotomy on demand (ROD) for patients with diffuse peritonitis.
In a retrospective analysis, the clinical course of 231 patients with diffuse peritonitis was analysed. The mean Mannheim Peritonitis Index (MPI) was 25.3. Overall lethality in this cohort was 14.3 %. In 214 patients, source control was successful during the index operation, and these patients were treated according to an on-demand strategy. For 178 of these patients, there was no demand for a relaparotomy, whereas 36 of these patients required further surgical interventions. Lethality for these subgroups was 9 % (no relaparotomy) and 27 % (relaparotomy), respectively.
This retrospective analysis confirms that an on-demand strategy is reasonable and feasible after successful source control and lavage. However, it still remains of clinical importance to identify parameters that may assist in selecting those patients who require a relaparotomy.
尽管有现代外科手术和重症监护理念,但弥漫性腹膜炎仍然是高发病率和高死亡率的主要来源。本研究的目的是严格评估按需再次剖腹手术(ROD)对弥漫性腹膜炎患者的价值。
在一项回顾性分析中,分析了231例弥漫性腹膜炎患者的临床病程。平均曼海姆腹膜炎指数(MPI)为25.3。该队列的总体死亡率为14.3%。在214例患者中,在初次手术期间源控制成功,这些患者按照按需策略进行治疗。其中178例患者无需再次剖腹手术,而其中36例患者需要进一步的手术干预。这些亚组的死亡率分别为9%(无需再次剖腹手术)和27%(再次剖腹手术)。
这项回顾性分析证实,在成功进行源控制和灌洗后,按需策略是合理且可行的。然而,识别可能有助于选择那些需要再次剖腹手术患者的参数仍然具有临床重要性。