Leibniz Institute of Polymer Research Dresden e.V., Max Bergmann Center of Biomaterials Dresden, Hohe Str. 6, 01069 Dresden, Germany.
Adv Mater. 2013 May 14;25(18):2606-10. doi: 10.1002/adma.201300691. Epub 2013 Apr 10.
Poly(ethylene glycol)-peptide- and glycosaminoglycan-peptide conjugates obtained by a regio-selective amino acid protection strategy are converted into cell-instructive hydrogel matrices capable of inducing morphogenesis in embedded human vascular endothelial cells and dorsal root ganglia.
通过区域选择性氨基酸保护策略获得的聚(乙二醇)-肽-和糖胺聚糖肽缀合物被转化为细胞指令性水凝胶基质,能够诱导嵌入的人血管内皮细胞和背根神经节的形态发生。