Life Sciences, Center for the Study of Biological Complexity, Virginia Commonwealth University, Richmond, VA, USA.
Chem Biodivers. 2013 Apr;10(4):596-9. doi: 10.1002/cbdv.201200417.
Myelinated axon nerve impulses travel 100 times more rapidly than impulses in non-myelinated axons. Increased speed is currently believed to be due to 'hopping' or 'saltatory propagation' along the axon, but the mechanism by which impulses flow has never been adequately explained. We have used modeling approaches to simulate a role for proton hopping in the space between the plasma membrane and myelin sheath as the mechanism of nerve action-potential flow.
有髓轴突神经冲动的传播速度比无髓轴突快 100 倍。目前认为，这种速度的增加是由于轴突上的“跳跃”或“跃式传播”。但是，冲动传播的机制从未得到充分解释。我们使用建模方法模拟了质子在质膜和髓鞘之间跳跃在神经动作电位流动机制中的作用。
