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本文引用的文献

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Evaluating the changes in alveolar permeability and lung ventilation in patients with chronic renal failure after haemodialysis using 99mTc-DTPA radioaerosol inhalation lung scan.利用99mTc-DTPA放射性气溶胶吸入肺扫描评估慢性肾衰竭患者血液透析后肺泡通透性和肺通气的变化。
Nucl Med Commun. 2003 Jul;24(7):825-8. doi: 10.1097/00006231-200307000-00013.
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Dialysis-related amyloidosis: importance of biocompatibility and age.透析相关性淀粉样变性:生物相容性和年龄的重要性
Nephrol Dial Transplant. 1998;13 Suppl 7:61-4. doi: 10.1093/ndt/13.suppl_7.61.
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Effect of oxygen on breathing irregularities during haemodialysis in patients with chronic uraemia.氧气对慢性尿毒症患者血液透析期间呼吸不规则的影响。
Eur Respir J. 1998 Aug;12(2):420-5. doi: 10.1183/09031936.98.12020420.
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Switch from conventional to high-flux membrane reduces the risk of carpal tunnel syndrome and mortality of hemodialysis patients.从传统膜转换为高通量膜可降低血液透析患者腕管综合征的风险和死亡率。
Kidney Int. 1997 Oct;52(4):1096-101. doi: 10.1038/ki.1997.434.
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Hemodialyzer mass transfer-area coefficients for urea increase at high dialysate flow rates. The Hemodialysis (HEMO) Study.在高透析液流速下,血液透析器对尿素的传质面积系数会增加。血液透析(HEMO)研究。
Kidney Int. 1997 Jun;51(6):2013-7. doi: 10.1038/ki.1997.274.
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The hemodialysis membranes: a historical perspective, current state and future prospect.血液透析膜:历史回顾、现状与未来展望
Semin Nephrol. 1997 May;17(3):196-213.
7
Effect of the dialysis membrane on mortality of chronic hemodialysis patients.透析膜对慢性血液透析患者死亡率的影响。
Kidney Int. 1996 Aug;50(2):566-70. doi: 10.1038/ki.1996.350.
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Nutrition in end-stage renal disease.
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Effect of the membrane biocompatibility on nutritional parameters in chronic hemodialysis patients.
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高通量与低通量透析膜对血液透析患者氧饱和度的影响。

Effects of high versus low flux membranes on o2 saturation in hemodialysis patients.

作者信息

Momeni Ali, Rouhi Hamid, Amiri Masoud

机构信息

Department of Internal Medicine, Shahrekord University of Medical Sciences, Shahrekord, IR Iran.

出版信息

Nephrourol Mon. 2013 Winter;5(1):683-6. doi: 10.5812/numonthly.5055. Epub 2012 Dec 15.

DOI:10.5812/numonthly.5055
PMID:23577331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3614324/
Abstract

BACKGROUND

Several studies have been carried out to evaluate the effects of dialysis on O2 saturation. While the dialysis procedure may lead to hypoxia under different circumstances, there are few studies available on the effects of membrane type on O2 saturation in these patients.

OBJECTIVES

This study was to appraise the effects of high and low flux membrane on pulse oxymetery in dialysis patients.

PATIENTS AND METHODS

In a cross-sectional evaluation, 43 hemodialysis patients without pulmonary disease were enrolled. Of this group, dialysis was performed by low and high flux membranes, and pulse oxymetery was applied before and after the procedures.

RESULTS

Mean age of the patients was 56.34 years. Of these patients, 23 (53.5%) and 20 (46.5%) were women and men, respectively. Type of membrane (high flux vs. low flux) did not show any significant effect on pulse oxymetery results (P > 0.05).

CONCLUSIONS

Due to the lack of a significant difference in pulse oxymetery and creation of hypoxia between two types of membranes in hemodialysis patients, as well as the high cost of high flux membrane as compared to the low flux membrane, we do not suggest the use of high flux membrane in dialysis.

摘要

背景

已经开展了多项研究来评估透析对氧饱和度的影响。虽然透析过程在不同情况下可能导致缺氧,但关于膜类型对这些患者氧饱和度影响的研究却很少。

目的

本研究旨在评估高通量膜和低通量膜对透析患者脉搏血氧饱和度的影响。

患者与方法

在一项横断面评估中,纳入了43例无肺部疾病的血液透析患者。在该组患者中,分别使用低通量膜和高通量膜进行透析,并在透析前后应用脉搏血氧测定法。

结果

患者的平均年龄为56.34岁。其中,女性23例(53.5%),男性20例(46.5%)。膜的类型(高通量与低通量)对脉搏血氧测定结果没有显著影响(P>0.05)。

结论

由于血液透析患者中两种类型的膜在脉搏血氧测定方面缺乏显著差异且不会造成缺氧,同时高通量膜相比低通量膜成本更高,因此我们不建议在透析中使用高通量膜。