Khoshnevis Jalaladin, Sobhiyeh Mohammad Reza, Lotfolahzadah Saran, Hoseinzadegan Shirazi Fatemah, Jalali Amir Hosein
Department of Vascular Surgery, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
Nephrourol Mon. 2013 Winter;5(1):697-701. doi: 10.5812/numonthly.5056. Epub 2012 Dec 15.
Dialysis vascular access complications are considered as significant causes of morbidity in chronic hemodialysis patients.
The aim of the present study was a comparison of axillary loop and straight grafts patency and its complications in hemodialysis access.
In this cohort study conducted at Shahid Beheshti Medical University, 77 patients who underwent placement of loop or straight access grafts were included. Demographics, primary and secondary patency rates and complications like thrombosis, infection, bleeding, steal syndrome and other complications were compared in these two groups. The collected data was analyzed by chi-square test, t-test, and logistic regression.
Primary patency rate in straight and loop groups after 1 month were 88.9% and 92.3% respectively (P = 0.721), and after 24 months were 31% and 55.5% respectively (P = 0.058). Secondary patency rate in straight and loop groups after 3 months were 75.6% and 92.3% respectively (P = 0.189), and after 24 months were 37.9% and 66.7% respectively (P = 0.044). The frequency of complications were the same among two methods of graft replacement and mal incidence of thrombosis, infection, delayed infection, pseudoaneurysm formation and steal syndrome occurrence ultimate graft failure and venous hypertension were not significantly different (P > 0.05).
Polytetrafluorethylene (PTFE) vascular graft seems to be an appropriate vascular access and is a promising alternative when upper extremity arteriovenous fistulas cannot be constructed. Additionally, there was no significant difference between the two groups for complications and early patency, but late patency was improved in loop group. More study is necessary for a conclusive assessment.
透析血管通路并发症被认为是慢性血液透析患者发病的重要原因。
本研究旨在比较腋部袢式移植物和直型移植物在血液透析通路中的通畅率及其并发症。
在设拉子医科大学进行的这项队列研究中,纳入了77例行袢式或直型移植物置入术的患者。比较了两组患者的人口统计学特征、初级和次级通畅率以及血栓形成、感染、出血、窃血综合征等并发症。采用卡方检验、t检验和逻辑回归分析收集的数据。
直型组和袢式组术后1个月的初级通畅率分别为88.9%和92.3%(P = 0.721),术后24个月分别为31%和55.5%(P = 0.058)。直型组和袢式组术后3个月的次级通畅率分别为75.6%和92.3%(P = 0.189),术后24个月分别为37.9%和66.7%(P = 0.044)。两种移植物置换方法的并发症发生率相同,血栓形成、感染、延迟感染、假性动脉瘤形成和窃血综合征的发生率以及最终移植物失败和静脉高压的发生率无显著差异(P > 0.05)。
聚四氟乙烯(PTFE)血管移植物似乎是一种合适的血管通路,当无法构建上肢动静脉内瘘时是一种有前景的替代方法。此外,两组在并发症和早期通畅率方面无显著差异,但袢式组的晚期通畅率有所提高。需要更多研究进行确定性评估。