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克罗恩病相关直肠阴道瘘:处理矛盾。

Rectovaginal fistulae in Crohn's disease: a management paradox.

机构信息

Department of Surgery, St Mark's Hospital, Harrow, UK, Department of Research Records, St Mark's Hospital, Harrow, UK.

出版信息

Colorectal Dis. 2000 May;2(3):154-8. doi: 10.1046/j.1463-1318.2000.00155.x.

Abstract

OBJECTIVE

Much has been written about the management of rectovaginal fistulae in Crohn's disease (CD), but there remains little or no consensus on the optimal therapeutic approach. This retrospective case review examined treatment and clinical outcome of women presenting with rectovaginal fistula between 1985 and 1995 in an attempt to clarify treatment guidelines.

PATIENTS AND METHODS

A total of 48 case notes was reviewed. Significant symptoms and signs were noted at presentation in 73% and 65% of women, respectively, and fistula classification revealed; three (6%) superficial, 36 (76%) transphincteric, six (12%) suprasphincteric and three (6%) unclassified.

RESULTS

Fifteen patients were initially treated conservatively, of whom 73% were eventually rendered asymptomatic and none required proctectomy. Of the remaining 33 fistulae, 12 were treated by laying open or seton insertion, 13 by local repair using transperineal proctotomy or advancement flaps, two by defunctioning alone, and six by proctectomy. Eighty-three percent of patients undergoing laying open or seton insertion, 77% following local repair and 50% following stoma were eventually rendered asymptomatic. The proctectomy rates were 42%, 15%, and 50% in these three groups, respectively.

CONCLUSION

The results of this study suggest that in the absence of significant symptoms, conservative management provides a good chance of fistula healing without need for proctectomy. However, if symptoms dictate the need for intervention, local repair provides a similar chance of success with a lower ultimate need for proctectomy than laying open or seton. Despite these broad generalities, this study highlights the difficulties we have in advising patients with proctovaginal fistulae in CD.

摘要

目的

关于克罗恩病(CD)直肠阴道瘘的治疗已经有很多报道,但对于最佳治疗方法仍存在很少或没有共识。本回顾性病例研究旨在明确治疗方案,分析 1985 年至 1995 年间就诊的女性直肠阴道瘘患者的治疗和临床结局。

患者和方法

共回顾了 48 例病历。73%和 65%的女性在就诊时分别有明显的症状和体征,瘘管分类为:3 例(6%)浅表,36 例(76%)经括约肌,6 例(12%)括约肌上,3 例(6%)未分类。

结果

15 例患者最初接受保守治疗,其中 73%最终无症状,无需行直肠切除术。其余 33 例瘘管中,12 例采用切开或挂线治疗,13 例采用经会阴直肠切开或推进皮瓣局部修复,2 例单纯采用结肠造口术,6 例采用直肠切除术。切开或挂线治疗的 83%、局部修复的 77%和结肠造口术的 50%患者最终无症状。这三组患者的直肠切除术率分别为 42%、15%和 50%。

结论

本研究结果表明,在无明显症状的情况下,保守治疗有很大机会治愈瘘管而无需行直肠切除术。然而,如果症状需要干预,局部修复的成功率与切开或挂线相似,但最终需要直肠切除术的可能性较小。尽管有这些一般原则,但本研究强调了我们在为 CD 合并直肠阴道瘘的患者提供建议时所面临的困难。

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