Lee H Y, Stretton T B, Barnes A M
Thorax. 1975 Feb;30(1):46-53. doi: 10.1136/thx.30.1.46.
Pulmonary function was studied in 55 patients with renal failure and no clinical or radiographic evidence of lung disease. A defect of gas transfer was found to be the rule due to a reduction in the diffusing capacity across the alveolar capillary membrane; this abnormality appeared to be related to the severity of the renal impairment. There was also a restrictive ventilatory defect which was more marked in male than in female patients. The significance of these findings is discussed, and attention is drawn to their relevance for patients receiving immuno-suppressive therapy or renal transplantation, in whom pulmonary complications are relatively common.
对55例肾衰竭患者进行了肺功能研究,这些患者无肺部疾病的临床或影像学证据。发现气体交换障碍是普遍现象,这是由于肺泡毛细血管膜的弥散能力降低所致;这种异常似乎与肾功能损害的严重程度有关。还存在限制性通气障碍,男性患者比女性患者更为明显。讨论了这些发现的意义,并提请注意它们与接受免疫抑制治疗或肾移植患者的相关性,这些患者肺部并发症相对常见。