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大象嗜内皮细胞疱疹病毒1A全基因组序列

Complete Genome Sequence of Elephant Endotheliotropic Herpesvirus 1A.

作者信息

Ling Paul D, Reid Jeffrey G, Qin Xiang, Muzny Donna M, Gibbs Richard, Petrosino Joseph, Peng Rongsheng, Zong Jian-Chao, Heaggans Sarah Y, Hayward Gary S

机构信息

Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.

出版信息

Genome Announc. 2013 Apr 11;1(2):e0010613. doi: 10.1128/genomeA.00106-13.

Abstract

Elephant endotheliotropic herpesvirus 1A is a member of the Proboscivirus genus and is a major cause of fatal hemorrhagic disease in endangered juvenile Asian elephants worldwide. Here, we report the first complete genome sequence from this genus, obtained directly from necropsy DNA, in which 60 of the 115 predicted genes are not found in any known herpesvirus.

摘要

大象内皮嗜性疱疹病毒1A是长鼻病毒属的一个成员,是全球濒危亚洲象幼崽致命出血性疾病的主要病因。在此,我们报告了该属的首个完整基因组序列,它直接从尸检DNA中获得,其中115个预测基因中的60个在任何已知疱疹病毒中均未发现。

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