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J Sleep Res. 2007 Dec;16(4):428-35. doi: 10.1111/j.1365-2869.2007.00612.x.
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Sleep. 2007 Mar;30(3):291-303. doi: 10.1093/sleep/30.3.291.
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Eur Respir J. 2007 Jun;29(6):1201-5. doi: 10.1183/09031936.00037106. Epub 2007 Mar 14.
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A high prevalence of sleep disordered breathing in men with mild symptomatic chronic heart failure due to left ventricular systolic dysfunction.因左心室收缩功能障碍导致的轻度症状性慢性心力衰竭男性患者中,睡眠呼吸障碍的高患病率。
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ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society.美国心脏病学会/美国心脏协会成人慢性心力衰竭诊断和治疗指南2005年更新版:美国心脏病学会/美国心脏协会实践指南工作组(更新2001年心力衰竭评估和管理指南写作委员会)报告:与美国胸科医师学会及国际心肺移植学会合作制定:得到心律学会认可。
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尼日利亚心力衰竭患者的打鼾与阻塞性睡眠呼吸暂停风险:患病率及临床相关性

Snoring and risk for obstructive sleep apnea among nigerians with heart failure: Prevalence and clinical correlates.

作者信息

Akintunde Adeseye A

机构信息

Department of Medicine, Division of Cardiology, Ladoke Akintola University of Technology Teaching Hospital, Ogbomosoc, Nigeria.

出版信息

Heart Views. 2013 Jan;14(1):17-21. doi: 10.4103/1995-705X.107115.

DOI:10.4103/1995-705X.107115
PMID:23580920
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3621219/
Abstract

BACKGROUND

Heart failure is an important cause of morbidity and mortality in developing nations like Nigeria. Sleep apnea and snoring has recently been recognized to be a cardiovascular risk factor. Sleep apnea is yet to be well studied among Africans with heart failure. We aimed to determine the prevalence of snoring and high risk for obstructive sleep apnea among Nigerians with stable heart failure.

MATERIALS AND METHODS

We studied 103 subjects that included 62 patients with heart failure and 41 control subjects. Demographic parameters and clinical examination were performed on the participants. The Berlin score and the Epworth Sleepiness Scale were administered for each participant. Echocardiography was done on all participants. Statistical analysis was done using Statistical Package for Social Sciences (SPSS) 17.0.

RESULTS

Snoring was reported in 48.4% of subjects with heart failure compared to 22.0% of control subjects ( P < 0.005). High risk for obstructive sleep apnea using the Berlin score was documented in 51.6% of heart failure subjects compared to 7.31% of controls. Excessive daytime somnolence occurred more in heart failure patients (51.6% vs. 9.8%, P < 0.05). Snorers tended to be older and were more likely to be obese than nonsnorers. Systolic blood pressure and fasting blood sugar were significantly higher among heart failure subjects with snoring than those without snoring (131.9 ± 19.2 vs. 119.2 ± 15.7 and 6.0 ± 0.8 vs. 5.4 ± 2.7, P < 0.005).

CONCLUSION

Heart failure seems to be associated with snoring and a high risk for obstructive sleep apnea among Africans with heart failure. Assessment for sleep disordered breathing should be incorporated into their routine clinical workup.

摘要

背景

心力衰竭是尼日利亚等发展中国家发病和死亡的重要原因。睡眠呼吸暂停和打鼾最近被认为是一种心血管危险因素。在患有心力衰竭的非洲人中,睡眠呼吸暂停尚未得到充分研究。我们旨在确定尼日利亚稳定心力衰竭患者中打鼾的患病率和阻塞性睡眠呼吸暂停的高风险。

材料与方法

我们研究了103名受试者,其中包括62名心力衰竭患者和41名对照受试者。对参与者进行了人口统计学参数和临床检查。为每位参与者进行了柏林评分和爱泼华嗜睡量表评估。对所有参与者进行了超声心动图检查。使用社会科学统计软件包(SPSS)17.0进行统计分析。

结果

心力衰竭受试者中有48.4%报告有打鼾,而对照受试者中为22.0%(P<0.005)。使用柏林评分,心力衰竭受试者中有51.6%被记录为阻塞性睡眠呼吸暂停高风险,而对照组为7.31%。心力衰竭患者白天过度嗜睡更为常见(51.6%对9.8%,P<0.05)。打鼾者往往年龄较大,比不打鼾者更易肥胖。心力衰竭打鼾受试者的收缩压和空腹血糖显著高于不打鼾者(131.9±19.2对119.2±15.7以及6.0±0.8对5.4±2.7,P<0.005)。

结论

心力衰竭似乎与心力衰竭非洲患者的打鼾和阻塞性睡眠呼吸暂停高风险有关。睡眠呼吸障碍评估应纳入其常规临床检查中。