Duru Serap, Yüceege Melike, Ardıç Sadık
Clinic of Chest Diseases, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.
Tuberk Toraks. 2013;61(1):71-5. doi: 10.5578/tt.3773.
Chitinase enzymes that hydrolize chitin and some articficial substrates are expressed in human despite lacking of the endogenous chitin within the body. Chitinases phatophysiological functions within human are not fully known. Recent evidence revealed that chitinases may have role into some processes of immune responses and inflammatory system. In this review, we discuss the role of chitinases in lung diseases based on the available information from the literature.
尽管人体内缺乏内源性几丁质，但能水解几丁质和一些人工底物的几丁质酶仍在人体中表达。几丁质酶在人体内的生理功能尚未完全明确。最近的证据表明，几丁质酶可能在免疫反应和炎症系统的某些过程中发挥作用。在本综述中，我们根据文献中的现有信息讨论几丁质酶在肺部疾病中的作用。
