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钙对哺乳动物组织体内铝诱导毒性的修饰作用。

Modifying effects of calcium on aluminum induced toxicity in mammalian tissues in vivo.

作者信息

Roy A K, Talukder G, Sharma A

机构信息

Department of Botany, University of Calcutta, India.

出版信息

Gegenbaurs Morphol Jahrb. 1990;136(2):155-61.

PMID:2358174
Abstract

Oral administration of calcium, following by aluminium or together with Al, has been found to counteract the toxic effects of the latter metal as observed in histological preparations of liver, brain, kidney, and bone of laboratory albino rats. No such improvement was seen if Ca was administered after Al. The protection afforded by Ca against Al toxicity may be due to the previous occupation by Ca ions of the binding sites of Al ions in the affected organs.

摘要

在实验室白化大鼠的肝脏、大脑、肾脏和骨骼的组织学标本中观察到,口服钙后再给予铝或钙与铝同时给予,已发现可抵消后一种金属的毒性作用。如果在铝之后给予钙,则未观察到这种改善。钙对铝毒性的保护作用可能是由于钙离子先前占据了受影响器官中铝离子的结合位点。

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