哺乳动物卫星 DNA：沉默的语言。
Mammalian satellite DNA: a speaking dumb.
机构信息
Institute of Cytology RAS, St. Petersburg, Russia.
出版信息
Adv Protein Chem Struct Biol. 2013;90:31-65. doi: 10.1016/B978-0-12-410523-2.00002-X.
Abstract
The tandemly organized highly repetitive satellite DNA is the main DNA component of centromeric/pericentromeric constitutive heterochromatin. For almost a century, it was considered as "junk DNA," only a small portion of which is used for kinetochore formation. The current review summarizes recent data about satellite DNA transcription. The possible functions of the transcripts are discussed.
摘要
串联组织的高度重复卫星 DNA 是着丝粒/着丝粒周围组成型异染色质的主要 DNA 成分。近一个世纪以来，它一直被认为是“垃圾 DNA”，只有一小部分用于形成动粒。本文综述了卫星 DNA 转录的最新数据，讨论了转录本的可能功能。
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