毛果芸香碱的眼部渗透：pH值对毛果芸香碱眼部渗透的影响。
Ocular penetration of pilocarpine: the effect of pH on the ocular penetration of pilocarpine.
作者信息
Ramer R M, Gasset A R
出版信息
Ann Ophthalmol. 1975 Feb;7(2):293-6.
PMID:235874
Abstract
Under the conditions of this study, tritiated pilocarpine was topically applied to rabbits, and the activity in the aqueous humor was measured at selected times. It was found that higher pH affords greater pilocarpine penetration. At pH 7.5, for example, penetration into the aqueous was twice as great as at pH 4.
摘要
在本研究条件下，将氚标记的毛果芸香碱局部应用于兔子，并在选定时间测量房水中的活性。发现较高的pH值能使毛果芸香碱的渗透能力更强。例如，在pH 7.5时，进入房水的渗透量是pH 4时的两倍。
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