Malone P S, Spitz L, Kiely E M, Brereton R J, Duffy P G, Ransley P G
Department of Paediatric Surgery, Hospitals for Sick Children, London, England.
J Pediatr Surg. 1990 Jun;25(6):679-80. doi: 10.1016/0022-3468(90)90362-d.
Twenty-seven patients with sacrococcygeal teratoma were followed for a mean period of 5 years (range, 2 to 12 years). Eleven (41%) had some form of functional impairment. Fecal and/or urinary incontinence was present in nine children and two had weakness of the lower limbs secondary to sciatic nerve palsy. Tumors with large intrapelvic extensions requiring an abdominoperineal approach for resection were associated with a higher incidence of functional sequelae (67%). It is recommended that patients with sacrococcygeal teratoma (particularly those with a presacral extension) be closely monitored for functional deficits so that early treatment can be instituted.
27例骶尾部畸胎瘤患者接受了平均5年(范围2至12年)的随访。11例(41%)有某种形式的功能障碍。9例儿童存在粪便和/或尿失禁,2例因坐骨神经麻痹继发下肢无力。需要经腹会阴入路切除的盆腔内巨大肿瘤与功能后遗症的发生率较高相关(67%)。建议对骶尾部畸胎瘤患者(尤其是那些有骶前延伸的患者)密切监测功能缺陷,以便能尽早开始治疗。