LoCicero J, Robinson P G, Fisher M
Department of Surgery, Northwestern University Medical School, Chicago, Ill. 60611-3008.
J Thorac Cardiovasc Surg. 1990 Jun;99(6):1059-62.
Chronic rejection of the lung in patients with heart-lung transplants has most often been associated with the development of obliterative bronchiolitis. Previously only one patient receiving a single-lung transplant suffered from the development of this problem. We describe a patient whose obliterative bronchiolitis developed 9 months after single-lung transplantation. Progressive deterioration occurred until his death from obliterative bronchiolitis at 21 months after transplantation. The functional and histologic changes are described and the possible mechanisms discussed.
心肺移植患者的慢性肺排斥反应最常与闭塞性细支气管炎的发展相关。此前仅有一名接受单肺移植的患者出现了这个问题。我们描述了一名患者，其闭塞性细支气管炎在单肺移植9个月后发生。病情逐渐恶化，直至移植后21个月因闭塞性细支气管炎死亡。文中描述了其功能和组织学变化，并讨论了可能的机制。
