Maybury Catriona M, Craythorne Emma, Martin Blanca
Department of Dermatology, Guys and St Thomas' Hospital Trust, London, UK.
BMJ Case Rep. 2013 Apr 16;2013:bcr2012008296. doi: 10.1136/bcr-2012-008296.
A 75-year-old retired nurse, originally from Barbados, presented to her general practitioner (GP) with a scaling ulcerated nodule on the left side of her nose. She was taking medication for type 2 diabetes, hypertension and glaucoma, but was otherwise well with no systemic symptoms. Her GP diagnosed a patch of eczema; however, a trial of topical steroids was not effective and she was referred to dermatology. A skin biopsy confirmed the clinical suspicion that this patient had a nodular basal cell carcinoma (BCC). BCCs account for 75% of all skin cancers; they very rarely metastasise, but can spread to invade local structures. Our patient has type VI skin. Skin cancer is rare in patients with skin type VI; however, in this group, morbidity and mortality are disproportionately high in relation to cancer incidence.
一位75岁的退休护士，原籍巴巴多斯，因左侧鼻部有一个鳞屑状溃疡结节就诊于她的全科医生（GP）。她正在服用治疗2型糖尿病、高血压和青光眼的药物，但除此之外身体状况良好，没有全身症状。她的全科医生诊断为一片湿疹；然而，外用类固醇试验无效，她被转诊至皮肤科。皮肤活检证实了临床怀疑，即该患者患有结节性基底细胞癌（BCC）。基底细胞癌占所有皮肤癌的75%；它们极少发生转移，但可扩散侵犯局部结构。我们的患者属于VI型皮肤。VI型皮肤的患者中皮肤癌罕见；然而，在这一群体中，发病率和死亡率与癌症发生率相比极不成比例地高。
