Suppr超能文献

鼻子上的一个溃疡结节。

An ulcerated nodule on the nose.

作者信息

Maybury Catriona M, Craythorne Emma, Martin Blanca

机构信息

Department of Dermatology, Guys and St Thomas' Hospital Trust, London, UK.

出版信息

BMJ Case Rep. 2013 Apr 16;2013:bcr2012008296. doi: 10.1136/bcr-2012-008296.

Abstract

A 75-year-old retired nurse, originally from Barbados, presented to her general practitioner (GP) with a scaling ulcerated nodule on the left side of her nose. She was taking medication for type 2 diabetes, hypertension and glaucoma, but was otherwise well with no systemic symptoms. Her GP diagnosed a patch of eczema; however, a trial of topical steroids was not effective and she was referred to dermatology. A skin biopsy confirmed the clinical suspicion that this patient had a nodular basal cell carcinoma (BCC). BCCs account for 75% of all skin cancers; they very rarely metastasise, but can spread to invade local structures. Our patient has type VI skin. Skin cancer is rare in patients with skin type VI; however, in this group, morbidity and mortality are disproportionately high in relation to cancer incidence.

摘要

一位75岁的退休护士,原籍巴巴多斯,因左侧鼻部有一个鳞屑状溃疡结节就诊于她的全科医生(GP)。她正在服用治疗2型糖尿病、高血压和青光眼的药物,但除此之外身体状况良好,没有全身症状。她的全科医生诊断为一片湿疹;然而,外用类固醇试验无效,她被转诊至皮肤科。皮肤活检证实了临床怀疑,即该患者患有结节性基底细胞癌(BCC)。基底细胞癌占所有皮肤癌的75%;它们极少发生转移,但可扩散侵犯局部结构。我们的患者属于VI型皮肤。VI型皮肤的患者中皮肤癌罕见;然而,在这一群体中,发病率和死亡率与癌症发生率相比极不成比例地高。

相似文献

1
An ulcerated nodule on the nose.鼻子上的一个溃疡结节。
BMJ Case Rep. 2013 Apr 16;2013:bcr2012008296. doi: 10.1136/bcr-2012-008296.
6
Combination Nasal Sidewall and Alar Defects.鼻侧壁和鼻翼联合缺损
Dermatol Surg. 2022 Jan 1;48(1):135-137. doi: 10.1097/DSS.0000000000002214.
8
Surface anatomy of the nose for the dermatologist.皮肤科医生鼻部的表面解剖。
J Cutan Med Surg. 2013 Mar-Apr;17(2):143-6. doi: 10.2310/7750.2012.12017.
9
Repair of a Large Multisubunit Nasal Defect.
Dermatol Surg. 2016 Feb;42(2):251-3. doi: 10.1097/DSS.0000000000000516.
10
Wound management in a patient with rhinophyma and basal cell carcinoma.
J Am Acad Dermatol. 2011 Jul;65(1):e11-2. doi: 10.1016/j.jaad.2011.01.021.

本文引用的文献

3
Inhibition of the hedgehog pathway in advanced basal-cell carcinoma.晚期基底细胞癌中刺猬信号通路的抑制作用。
N Engl J Med. 2009 Sep 17;361(12):1164-72. doi: 10.1056/NEJMoa0905360. Epub 2009 Sep 2.
4
Guidelines for the management of basal cell carcinoma.基底细胞癌管理指南。
Br J Dermatol. 2008 Jul;159(1):35-48. doi: 10.1111/j.1365-2133.2008.08666.x.
5
Skin cancer in skin of color.有色人种皮肤的皮肤癌
J Am Acad Dermatol. 2006 Nov;55(5):741-60; quiz 761-4. doi: 10.1016/j.jaad.2005.08.063.
6
Molecular aetiology and pathogenesis of basal cell carcinoma.
Br J Dermatol. 2005 Jun;152(6):1108-24. doi: 10.1111/j.1365-2133.2005.06587.x.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验