Garite T J, Bentley D L, Hamer C A, Porto M L
Department of Obstetrics and Gynecology, University of California, Irvine.
Obstet Gynecol. 1990 Jul;76(1 Suppl):56S-59S.
The frequency of uterine contractions has been shown to be increased during the 24-48 hours before the diagnosis of preterm labor in singleton gestations. Experience has indicated that there is also an increase in baseline uterine activity in twin gestations beyond that seen in women with singleton pregnancies. In this study, patients with twin gestations (39), triplet pregnancies (20), and quadruplets (ten) were monitored in the home daily for uterine activity. The results indicate that uterine activity was increased slightly within 48 hours of the onset of their initial preterm labor episode and significantly increased over baseline during the 24 hours preceding the diagnosis of preterm labor. This uterine activity led to evaluation for preterm labor before advanced dilatation occurred so that the majority of patients continued their pregnancy for more than 48 hours after diagnosis. Tocolytics did not have an effect on the crescendo of uterine activity preceding preterm labor. In this study, the crescendo of uterine activity occurred in multifetal gestations within 24 hours of preterm labor, as has been described for singleton pregnancies.
单胎妊娠早产诊断前24 - 48小时，子宫收缩频率已显示增加。经验表明，双胎妊娠的子宫基线活动也高于单胎妊娠女性。在本研究中，对双胎妊娠（39例）、三胎妊娠（20例）和四胎妊娠（10例）患者进行居家每日子宫活动监测。结果表明，在首次早产发作开始后的48小时内，子宫活动略有增加，在早产诊断前24小时内较基线显著增加。这种子宫活动导致在宫颈扩张进展之前对早产进行评估，从而使大多数患者在诊断后继续妊娠超过48小时。宫缩抑制剂对早产前子宫活动的增强没有影响。在本研究中，多胎妊娠早产前24小时内子宫活动增强，这与单胎妊娠的情况相同。
