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术中使用吲哚菁绿血管造影术以减少腹壁重建中伤口愈合并发症

Use of intraoperative indocyanin-green angiography to minimize wound healing complications in abdominal wall reconstruction.

作者信息

Patel Ketan M, Bhanot Parag, Franklin Brenton, Albino Frank, Nahabedian Maurice Y

机构信息

Department of Plastic Surgery.

出版信息

J Plast Surg Hand Surg. 2013 Dec;47(6):476-80. doi: 10.3109/2000656X.2013.787085. Epub 2013 Apr 18.

Abstract

Complication rates following abdominal wall reconstruction (AWR) remain high. Early complications are related to skin necrosis and delayed healing, whereas late complications are related to recurrence. When concomitant body contouring procedures are performed, complication rates can be further increased. It is hypothesised that fluorescent angiography using indocyanin green (ICG) can identify poorly perfused tissues and thus reduce the incidence of delayed healing. A retrospective review was conducted of all patients who underwent AWR with concomitant panniculectomy from 2007-2012. Intraoperative ICG angiography with the SPY system (LifeCell Corp.) was used to determine the amount of resection for body contouring in patients who underwent reconstruction in a cohort of patients. SPY-Q was used to assess relative perfusion of analysed areas. Preoperative, postoperative, and operative details were analyzed. Seventeen patients met inclusion criteria, 12 patients were included in the non-ICG cohort, while five patients were included in the ICG cohorts. Wound-healing complications occurred in 5/12 (42%) patients in the non-ICG cohort vs 1/5 (20%) of the ICG cohorts. A description of the sole patient with complications in the ICG cohort is illustrated. Operative debridement and wound infection development occurred more frequently in the non-ICG cohort compared with the ICG cohort (17%, 17% vs 0%, 0%, respectively). Average time to wound healing was 41.1 days. Intraoperative ICG angiography can accurately detect perfusion abnormalities and can decrease wound healing related complications in complex hernia repair with concomitant panniculectomy. Assessing and ensuring skin viability can decrease the need for operative debridement.

摘要

腹壁重建(AWR)后的并发症发生率仍然很高。早期并发症与皮肤坏死和愈合延迟有关,而晚期并发症与复发有关。当同时进行身体塑形手术时,并发症发生率可能会进一步增加。据推测,使用吲哚菁绿(ICG)的荧光血管造影可以识别灌注不良的组织,从而降低愈合延迟的发生率。对2007年至2012年期间接受AWR并同时行腹壁成形术的所有患者进行了回顾性研究。在一组接受重建的患者中,术中使用SPY系统(LifeCell公司)进行ICG血管造影,以确定身体塑形的切除量。使用SPY-Q评估分析区域的相对灌注情况。分析术前、术后及手术细节。17例患者符合纳入标准,12例患者纳入非ICG队列,5例患者纳入ICG队列。非ICG队列中的5/12(42%)患者出现伤口愈合并发症,而ICG队列中的1/5(20%)患者出现此类并发症。文中对ICG队列中唯一出现并发症的患者进行了描述。与ICG队列相比,非ICG队列中手术清创和伤口感染的发生率更高(分别为17%、17%和0%、0%)。伤口愈合的平均时间为41.1天。术中ICG血管造影可以准确检测灌注异常,并可减少复杂疝修补术并同时行腹壁成形术时与伤口愈合相关的并发症。评估并确保皮肤活力可以减少手术清创的需求。

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