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吲哚菁绿在腹疝修补的组件分离技术中减轻伤口并发症的作用——我们的早期经验。

Role of Indocyanine Green to Mitigate Wound Complications in Component Separation Technique for Ventral Hernia Repair-Our Early Experience.

机构信息

Department of General Surgery, Seth GSMC and KEM Hospital, Mumbai, India.

出版信息

World J Surg. 2021 Oct;45(10):3073-3079. doi: 10.1007/s00268-021-06210-4. Epub 2021 Jun 26.

Abstract

BACKGROUND

The ease of the anterior component separation technique (ACST) makes it an attractive surgical option for ventral hernia repairs (VHR). Incorporation of indocyanine green-fluorescence angiography (ICG-FA) to map soft tissue perfusion during open ACST is an effective way to minimize the wound complications. This study aims to evaluate the impact of adoption of ICG-FA on wound-related complications following open ACST in VHR.

METHODS

We performed a retrospective review of patients who underwent VHR with the open ACST at a single centre between March 2018 and July 2020. The study comprised of consecutive cases of open ACST with onlay meshplasty done before (March 2018-April 2019) and after (May 2019 to July 2020) implementation of ICG-FA for intra-operative perfusion mapping of subcutaneous tissue and skin.

RESULTS

The pre-ICG group and post-ICG group were similar in terms of baseline patient demographics and peri-operative details. The rate of surgical site occurrence's was higher in the pre-ICG group, but this result was not statistically significant (46% vs. 26%; p value 0.189). Skin necrosis, however, was observed in significantly less patients of the post-ICG cohort (29% vs. 5%; p value 0.045).

CONCLUSION

This study demonstrates the effectiveness of perfusion mapping by the use of ICG angiography to determine potential areas of decreased perfusion and thereby minimize wound complications. Using ICG-FA to guide removal of at-risk tissue to minimize wound complications may substantially improve the patients outcome.

摘要

背景

前侧组件分离技术(ACST)操作简单,因此成为腹壁疝修补术(VHR)的一种有吸引力的手术选择。在开放式 ACST 中使用吲哚菁绿荧光血管造影(ICG-FA)来绘制软组织灌注图是减少伤口并发症的有效方法。本研究旨在评估在 VHR 中采用 ICG-FA 对开放式 ACST 后与伤口相关的并发症的影响。

方法

我们对 2018 年 3 月至 2020 年 7 月在一家中心接受 VHR 开放式 ACST 的患者进行了回顾性研究。该研究包括连续的开放式 ACST 病例,在实施 ICG-FA 之前(2018 年 3 月至 2019 年 4 月)和之后(2019 年 5 月至 2020 年 7 月)进行,用于术中皮下组织和皮肤灌注的映射。

结果

在基线患者人口统计学和围手术期细节方面,ICG 组和非 ICG 组相似。ICG 组的手术部位发生率较高,但无统计学意义(46%比 26%;p 值为 0.189)。然而,在 ICG 组中观察到皮肤坏死的患者明显减少(29%比 5%;p 值为 0.045)。

结论

本研究证明了使用 ICG 血管造影术进行灌注映射以确定潜在的灌注减少区域并最小化伤口并发症的有效性。使用 ICG-FA 来指导切除有风险的组织以最小化伤口并发症可能会显著改善患者的预后。

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