Reshetnikov O V, Openko T G, Simonova G I, Kurilovich S A, Maliushina S K, Ragino Iu I, Voevoda M I
Vopr Onkol. 2012;58(5):644-8.
In a prospective study the risk of subsequent gastric cancer (GC) was assessed in persons aged 45-69 over 5 years after the initial testing with a set of serological tests (pepsinogen I, pepsinogen II, gastrin-17, antibodies to Helicobacter pylori). The presence of gastric atrophy markers was a significant predictor of GC in the forthcoming years. Non-invasive techniques may be used in the formation of high-risk groups, followed by GC active surveillance.
在一项前瞻性研究中,对45至69岁的人群在初次检测(采用一组血清学检测,即胃蛋白酶原I、胃蛋白酶原II、胃泌素-17、幽门螺杆菌抗体)后的5年里后续患胃癌(GC)的风险进行了评估。胃萎缩标志物的存在是未来几年患GC的重要预测指标。非侵入性技术可用于高危人群的形成,随后进行GC主动监测。