Neuro-Urology Department of Tenon Hospital, University Pierre and Marie Curie, Paris, France; Group of Clinical Research in Neuro-Urology, University Pierre and Marie Curie, Paris, France; Obstetrics and Gynecology Department, University Paris 11, Clamart, France.
Int J Urol. 2013 Nov;20(11):1124-9. doi: 10.1111/iju.12122. Epub 2013 Apr 21.
To assess the predictive value of a simple clinical test (posterior vaginal wall pull down maneuver) in the diagnosis of intrinsic sphincter deficiency.
The present prospective study included 62 women suffering from stress urinary incontinence. Every patient underwent a urogynecological examination including multichannel urodynamic testing (cystometry, urethral pressure profile, Valsalva Leak Point Pressure measurement) and a clinical examination including posterior vaginal wall pull down maneuver. Posterior vaginal wall pull down maneuver was carried out with the bladder filled with 400 mL of saline in a supine position, and was obtained by means of a split speculum allowing gentle pull down traction of the posterior vaginal wall. Posterior vaginal wall pull down maneuver was considered as positive when a urine leak was observed during the manoeuvre. Intrinsic sphincter deficiency was urodynamically defined by maximum urethral closure pressure ≤20 cmH2 O. Correlations between positive/negative posterior vaginal wall pull down maneuver and urodynamic intrinsic sphincter deficiency were calculated.
There was a statistical correlation between age and low maximum urethral closure pressure (P < 0.0001), and between low maximum urethral closure pressure and positive posterior vaginal wall pull down maneuver (P < 0.0001). Regarding the intrinsic sphincter deficiency diagnosis, the posterior vaginal wall pull down maneuver positive predictive value was 94.67% and the negative predictive value was 95.4%, with a specificity of 97.6% and sensitivity of 90%.
Posterior vaginal wall pull down maneuver is a reliable clinical test, easy to carry out, inexpensive and without significant risk. This test allows the diagnosis of intrinsic sphincter deficiency in women suffering from stress urinary incontinence, thus avoiding further invasive urodynamic testing (urethral pressure profile, Valsalva Leak Point Pressure measurement) in women with genuine stress urinary incontinence. Furthermore, it is helpful when choosing the type of sling procedure (retropubic vs transobturator) when a surgery is planned.
评估一种简单的临床检查(后阴道壁下拉操作)在诊断内括约肌缺陷中的预测价值。
本前瞻性研究纳入 62 例患有压力性尿失禁的女性。每位患者均接受了妇科泌尿科检查,包括多通道尿动力学检查(膀胱测压、尿道压力描记、Valsalva 漏尿点压力测量)和临床检查,包括后阴道壁下拉操作。患者取仰卧位,膀胱内注入 400ml 生理盐水后进行后阴道壁下拉操作,使用阴道扩张器轻柔地向下牵拉后阴道壁。当操作过程中观察到尿液泄漏时,认为后阴道壁下拉操作阳性。内括约肌缺陷通过最大尿道闭合压≤20cmH2O 进行尿动力学定义。计算后阴道壁下拉操作阳性/阴性与尿动力学内括约肌缺陷之间的相关性。
年龄与最大尿道闭合压降低之间存在统计学相关性(P<0.0001),最大尿道闭合压降低与后阴道壁下拉操作阳性之间也存在统计学相关性(P<0.0001)。对于内括约肌缺陷的诊断,后阴道壁下拉操作的阳性预测值为 94.67%,阴性预测值为 95.4%,特异性为 97.6%,敏感性为 90%。
后阴道壁下拉操作是一种可靠的临床检查方法,易于操作,价格低廉,且无明显风险。该检查可用于诊断患有压力性尿失禁的女性中的内括约肌缺陷,从而避免对真正患有压力性尿失禁的女性进行进一步的侵入性尿动力学检查(尿道压力描记、Valsalva 漏尿点压力测量)。此外,当计划手术时,它有助于选择吊带手术类型(耻骨后 vs 经闭孔)。