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左心房纵向应变参数可预测二尖瓣手术后的术后持续性房颤:一项斑点追踪超声心动图研究。

Left atrial longitudinal strain parameters predict postoperative persistent atrial fibrillation following mitral valve surgery: a speckle tracking echocardiography study.

作者信息

Candan Ozkan, Ozdemir Nihal, Aung Soe Moe, Dogan Cem, Karabay Can Yucel, Gecmen Cetin, Omaygenç Onur, Güler Ahmet

机构信息

Cardiology Clinic, Kartal Kosuyolu Heart & Research Hospital, Istanbul, Turkey.

出版信息

Echocardiography. 2013 Oct;30(9):1061-8. doi: 10.1111/echo.12222. Epub 2013 Apr 19.

DOI:10.1111/echo.12222
PMID:23600893
Abstract

Postoperative atrial fibrillation (POAF) is common after cardiac surgery and is associated with increased morbidity, mortality, and prolonged hospital stay. Speckle tracking echocardiography (STE) has been applied recently for evaluation of LA function. The purpose of this study was to examine whether left atrial longitudinal strain measured by STE is a predictor for the development of POAF following mitral valve surgery for severe mitral regurgitation. We studied 53 patients undergoing mitral valve surgery in sinus rhythm at the time of surgery. Echocardiography with evaluation of LA strain by STE was performed. Detection of POAF was based on documentation of AF episodes by continuous telemetry throughout hospitalization. Patients who did not develop POAF were taken as group 1 and those who had POAF constituted group 2. The echocardiographic and clinical predictors of POAF were investigated. POAF occurred in 28.3% of subjects. Mean age, LAVi and BNP were found higher in group 2 while peak atrial longitudinal strain (PALS) (13.9 ± 3.8% vs. 24.8 ± 7.3%; P < 0.001), peak atrial contraction strain (PACS) (7.6 ± 1.95% vs. 11.3 ± 3.5%; P < 0.001) were significantly lower. By multivariate logistic regression analysis, PALS and LAVi were independent predictor of POAF development. LA longitudinal strain was found to predict POAF in patients undergoing mitral valve surgery. It could be used to better identify patients at greater risk of developing POAF, and thus to guide in risk stratification and to take appropriate intensive prophylactic therapy.

摘要

术后心房颤动(POAF)在心脏手术后很常见,与发病率增加、死亡率升高及住院时间延长相关。斑点追踪超声心动图(STE)最近已被应用于评估左心房功能。本研究的目的是探讨通过STE测量的左心房纵向应变是否是重度二尖瓣反流二尖瓣手术后发生POAF的预测指标。我们研究了53例手术时处于窦性心律的二尖瓣手术患者。进行了通过STE评估左心房应变的超声心动图检查。POAF的检测基于整个住院期间连续遥测记录的房颤发作情况。未发生POAF的患者作为第1组,发生POAF的患者构成第2组。研究了POAF的超声心动图和临床预测指标。28.3%的受试者发生了POAF。发现第2组的平均年龄、左心房容积指数(LAVi)和脑钠肽(BNP)较高,而心房纵向应变峰值(PALS)(13.9±3.8%对24.8±7.3%;P<0.001)、心房收缩应变峰值(PACS)(7.6±1.95%对11.3±3.5%;P<0.001)显著较低。通过多因素逻辑回归分析,PALS和LAVi是POAF发生的独立预测指标。发现左心房纵向应变可预测二尖瓣手术患者发生POAF。它可用于更好地识别发生POAF风险更高的患者,从而指导风险分层并采取适当的强化预防性治疗。

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