Department of Urology, Institute of Nephro-Urology, Bangalore, Karnataka, India.
Int J Urol. 2013 Dec;20(12):1199-203. doi: 10.1111/iju.12158. Epub 2013 Apr 21.
To compare lingual and buccal mucosa graft urethroplasty for anterior urethral stricture with respect to intraoperative, postoperative parameters and urethroplasty outcome.
From January 2011 to December 2011, a total of 30 patients with anterior urethral stricture whereas group 2 underwent dorsal onlay buccal mucosa graft urethroplasty. Patients were evaluated for postoperative, tongue protrusion, oral opening, and difficulty in speech and swallowing pain score. Surgical outcome was evaluated with pre- and postoperative work-up involving retrograde urethrogram, uroflow and urethroscopy.
Mean age, stricture length and overall pain score were comparable in two groups. All the patients were mostly pain free by postoperative day 7. Group 1 patients had significant difficulty in speech and delayed return to normal diet as compared with group 2. The group 2 patients had a significant reduction in oral opening for the first week after surgery. In group 1, approximately 20% patients (with bilateral lingual grafts and stricture length >7 cm) complained of a change in speech character with restricted tongue movement in the long term, whereas there was no significant long-term morbidity in group 2. At mean follow up of 14.5 months, urethroplasty outcome was comparable in the two groups with one failure in group 1, and two failures in group 2.
Lingual mucosa graft urethroplasty provides outcomes equivalent to those of buccal mucosa graft urethroplasty. Postoperative morbidity and long-term change in speech make it a second choice for strictures >7 cm, only for cases where buccal mucosa graft is unavailable.
比较舌黏膜和颊黏膜移植尿道成形术治疗前尿道狭窄的术中、术后参数和尿道成形术结果。
2011 年 1 月至 2011 年 12 月,共有 30 例前尿道狭窄患者,其中 15 例接受舌黏膜游离移植尿道成形术(组 1),15 例接受颊黏膜游离移植尿道成形术(组 2)。术后评估患者的舌突出、张口度、言语困难和吞咽疼痛评分。采用逆行尿道造影、尿流率和尿道镜检查对术前和术后检查进行手术结果评估。
两组患者的平均年龄、狭窄长度和总疼痛评分相当。所有患者在术后第 7 天大多无疼痛。与组 2 相比,组 1 患者的言语困难和恢复正常饮食的时间明显延迟。组 2 患者术后第 1 周张口度明显减小。在组 1 中,约 20%的患者(双侧舌黏膜移植且狭窄长度>7cm)在长期随访中出现言语特征改变,舌运动受限,而组 2 无明显长期并发症。在平均随访 14.5 个月时,两组的尿道成形术结果相当,组 1 中有 1 例失败,组 2 中有 2 例失败。
舌黏膜移植尿道成形术的结果与颊黏膜移植尿道成形术相当。术后并发症和长期言语改变使其成为狭窄>7cm 的二线选择,仅适用于颊黏膜移植不可用的病例。