Suppr超能文献

儿童气管修复:随着滑动气管成形术的出现死亡率降低

Tracheal repair in children: reduction of mortality with advent of slide tracheoplasty.

作者信息

Yong Matthew S, d'Udekem Yves, Robertson Colin F, Butt Warwick, Brizard Christian P, Konstantinov Igor E

机构信息

Department of Cardiothoracic Surgery, Royal Children's Hospital, Melbourne, Victoria, Australia; The University of Melbourne, Melbourne, Victoria, Australia; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.

出版信息

ANZ J Surg. 2014 Oct;84(10):748-54. doi: 10.1111/ans.12132. Epub 2013 Apr 18.

Abstract

BACKGROUND

Severe tracheal stenosis is a rare life-threatening condition that often requires early surgical intervention. The management of this anomaly has been associated with significant mortality and morbidity. We describe our experience with repair of this condition.

METHODS

From 1986 to 2011, 20 patients underwent repair of tracheal stenosis at the Royal Children's Hospital (median age 4.9 months) and were retrospectively reviewed.

RESULTS

Tracheal repair techniques used were as follows: patch tracheoplasty (n=8; 40%, 8 out of 20), slide tracheoplasty (n=7; 35%, 7 out of 20), end-to-end anastomosis (n=5; 25%, 5 out of 20). Six patients (30%, 6 out of 20) had coexisting congenital intracardiac anomalies. There were 12 pulmonary artery sling (60%, 12 out of 20) patients. Overall operative mortality was 15% (n=3; 3 out of 20). Operative mortality was 20% (n=2; 2 out of 10) from 1986 to 2001 and decreased to 10% (n=1; 1 out of 10) from 2002 to 2011. All early deaths occurred in patients who had undergone patch tracheoplasty. Since 2004, there were no operative deaths. Seven patients (35%, 7 out of 20) required tracheal reintervention postoperatively. There were three late deaths (17.6%, 3 out of 17) at 8, 9 and 22 months after surgery. At last follow-up (mean 5.3±6.6 years; range 1 month to 18 years), all 14 survivors remained asymptomatic.

CONCLUSIONS

Repair of tracheal stenosis in children has been associated with high morbidity and mortality. Since the introduction of slide tracheoplasty, a multidisciplinary team approach and abandonment of patch tracheoplasty, the mortality has been reduced. Survival beyond 2 years after surgery is associated with an excellent outcome.

摘要

背景

严重气管狭窄是一种罕见的危及生命的疾病,通常需要早期手术干预。这种异常情况的治疗一直伴随着显著的死亡率和发病率。我们描述了我们在修复这种疾病方面的经验。

方法

从1986年到2011年,20例患者在皇家儿童医院接受了气管狭窄修复手术(中位年龄4.9个月),并进行了回顾性研究。

结果

所采用的气管修复技术如下:补片气管成形术(n = 8;40%,20例中的8例),滑动气管成形术(n = 7;35%,20例中的7例),端端吻合术(n = 5;25%,20例中的5例)。6例患者(30%,20例中的6例)合并先天性心脏内异常。有12例肺动脉吊带患者(60%,20例中的12例)。总体手术死亡率为15%(n = 3;20例中的3例)。1986年至2001年手术死亡率为20%(n = 2;10例中的2例),2002年至2011年降至10%(n = 1;10例中的1例)。所有早期死亡均发生在接受补片气管成形术的患者中。自2004年以来,无手术死亡病例。7例患者(35%,20例中的7例)术后需要再次进行气管干预。术后8、9和22个月有3例晚期死亡(17.6%,17例中的3例)。在最后一次随访时(平均5.3±6.6年;范围1个月至18年),所有14名幸存者均无症状。

结论

儿童气管狭窄修复手术一直伴随着较高的发病率和死亡率。自从引入滑动气管成形术、多学科团队方法以及放弃补片气管成形术后,死亡率有所降低。术后存活超过2年与良好的预后相关。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验