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优化一期骶神经调节评估在非梗阻性慢性尿潴留中的持续时间。

Optimizing the duration of assessment of stage-1 sacral neuromodulation in nonobstructive chronic urinary retention.

机构信息

Department of Uro-neurology, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

出版信息

Neuromodulation. 2014 Jan;17(1):66-70; discussion 70-1. doi: 10.1111/ner.12017. Epub 2013 Apr 19.

Abstract

OBJECTIVES

The duration of test stimulation using two-stage sacral neuromodulation (SNM) is not studied. This study will determine the restoration of normal bladder sensation and resultant voiding in chronic urinary retention (CUR) after stage-1 SNM.

MATERIALS AND METHODS

Two-stage SNM used in 24 female patients with CUR. After stage-1 SNM, patients were assessed over an eight-week period and asked to record the restoration of normal bladder sensation and voiding. Qualitative and quantitative statistics were used to assess the outcomes and the influence of prognostic factors.

RESULTS

The mean age of patients was 37.0 ± 9.7 years. Normal bladder sensation was restored on the same day as switching on the battery after stage-1 in seven patients (29.2%), while in 17 patients it occurred between day 2-31 (mean: nine days). Similarly, the mean onset of voiding was also nine days (range: 2-31 days). After day 15, 21% of patients voided. The mean lag time between the restoration of bladder sensation and voiding was 3.6 days. By day 17, a cumulative percentage of 90% of patients had a normalized bladder sensation and 80% had commenced voiding. Infection of the externalized lead occurred in only one case. There were no correlations between the outcome parameters with age (p > 0.05), symptom duration, or concomitant diagnosis of overactive bladder or chronic pelvic pain (p = 0.418, p = 0.114).

CONCLUSION

Stage-1 SNM may be left in situ for up to four weeks to ensure the maximum chance of restoring normal bladder function in this complex group of patients.

摘要

目的

两阶段骶神经调节(SNM)的测试刺激持续时间尚未研究。本研究将确定在慢性尿潴留(CUR)中,第一阶段 SNM 后正常膀胱感觉的恢复和随之而来的排尿情况。

材料和方法

在 24 名 CUR 女性患者中使用两阶段 SNM。在第一阶段 SNM 后,患者在八周的时间内进行评估,并要求记录正常膀胱感觉的恢复和排尿情况。使用定性和定量统计来评估结果和预后因素的影响。

结果

患者的平均年龄为 37.0±9.7 岁。在七名患者(29.2%)中,第一阶段 SNM 后打开电池的同一天恢复了正常膀胱感觉,而在 17 名患者中,恢复时间在第 2-31 天之间(平均:9 天)。同样,平均排尿开始时间也是 9 天(范围:2-31 天)。第 15 天后,21%的患者开始排尿。膀胱感觉恢复和排尿之间的平均滞后时间为 3.6 天。到第 17 天,90%的患者有正常的膀胱感觉,80%的患者开始排尿。仅在一例患者中发生外部化导联感染。结果参数与年龄(p>0.05)、症状持续时间或并存的膀胱过度活动症或慢性盆腔疼痛无相关性(p=0.418,p=0.114)。

结论

第一阶段 SNM 可以留在原位长达四周,以确保在这组复杂患者中最大程度地恢复正常膀胱功能的机会。

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