Jairam Ranjana, Drossaerts Jamie, van Koeveringe Gommert, van Kerrebroeck Philip
Department of Urology, Maastricht University Medical Centre (MUMC+), Maastricht, The Netherlands.
Urol Int. 2017;99(1):51-55. doi: 10.1159/000456079. Epub 2017 May 6.
The study aimed to evaluate whether the duration of complaints in patients with overactive bladder syndrome or non-obstructive urinary retention predicts the outcome of sacral neuromodulation (SNM).
All patients that underwent a SNM test period evaluation between 2011 and 2014, were included in this study. The duration of complaints was listed in 3 categories: (a) 0-5 years, (b) 5-10 years and (c) 10 years or longer. Analyses with chi square tests were performed to evaluate whether the duration of complaints are associated with outcome of SNM.
In total, 130 patients were included. Most patients had a complaint duration of 0-5 years (n = 60). The test period was successful in 56% (n = 74) of the total group. Analyses showed that the duration of complaints is not significantly associated with outcome of SNM (p = 0.752), even when subdivided per indication, and also when possible confounders such as age at test and indication are taken into account (p = 0.720).
Based on the results of this study, there is no relationship between duration of complaints and SNM outcome. SNM seems to remain a feasible treatment option, despite of possible anatomical or physiological changes within the lower urinary tract.
本研究旨在评估膀胱过度活动症或非梗阻性尿潴留患者的症状持续时间是否可预测骶神经调节（SNM）的治疗效果。
本研究纳入了2011年至2014年间接受SNM测试期评估的所有患者。症状持续时间分为3类：（a）0 - 5年，（b）5 - 10年，（c）10年或更长时间。采用卡方检验进行分析，以评估症状持续时间是否与SNM的治疗效果相关。
共纳入130例患者。大多数患者的症状持续时间为0 - 5年（n = 60）。在整个研究组中，测试期成功率为56%（n = 74）。分析表明，症状持续时间与SNM的治疗效果无显著相关性（p = 0.752），即使按适应症细分，以及考虑到测试时年龄和适应症等可能的混杂因素时也是如此（p = 0.720）。
基于本研究结果，症状持续时间与SNM治疗效果之间没有关系。尽管下尿路可能存在解剖或生理变化，但SNM似乎仍是一种可行的治疗选择。
