IADI Laboratory, INSERM-U947, Nancy-University, Allée du Morvan, 54500 Vandoeuvre-les-Nancy, France.
Eur J Radiol. 2013 Aug;82(8):1201-6. doi: 10.1016/j.ejrad.2013.02.020. Epub 2013 Apr 17.
Evaluate the capability of different Computed Tomography scanners to determine urinary stone compositions based on CT attenuation values and to evaluate potential differences between each model.
241 human urinary stones were obtained and their biochemical composition determined. Four different CT scanners (Siemens, Philips, GEMS and Toshiba) were evaluated. Mean CT-attenuation values and the standard deviation were recorded separately and compared with a t-paired test.
For all tested CT scanners, when the classification of the various types of stones was arranged according to the mean CT-attenuation values and to the confidence interval, large overlappings between stone types were highlighted. The t-paired test showed that most stone types could not be identified. Some types of stones presented mean CT attenuation values significantly different from one CT scanner to another. At 80kV, the mean CT attenuation values obtained with the Toshiba Aquilion were significantly different from those obtained with the Siemens Sensation. On the other hand, mean values obtained with the Philips Brilliance were all significantly equal to those obtained with the Siemens Sensation and with the Toshiba Aquilion. At 120kV mean CT attenuation values of uric acid, cystine and struvite stones obtained with the Philips model are significantly different from those obtained with the Siemens and the Toshiba but equal to those obtained with the GE 64.
According to our study, there is a great variability when different brands and models of scanners are compared directly. Furthermore, the CT scan analysis and HU evaluation appears to gather insufficient information in order to characterize and identify the composition of renal stones.
评估不同 CT 扫描仪基于 CT 衰减值来确定尿结石成分的能力，并评估各型号之间的潜在差异。
获得 241 个人类尿结石，并确定其生化组成。评估了 4 种不同的 CT 扫描仪（西门子、飞利浦、GEMS 和东芝）。分别记录平均 CT 衰减值和标准差，并进行 t 配对检验。
对于所有测试的 CT 扫描仪，当根据平均 CT 衰减值和置信区间对各种类型的结石进行分类时，突出显示了结石类型之间的大量重叠。t 配对检验表明，大多数结石类型无法识别。一些类型的结石的平均 CT 衰减值与一台 CT 扫描仪与另一台之间存在显著差异。在 80kV 下，东芝 Aquilion 获得的平均 CT 衰减值与西门子 Sensation 获得的值显著不同。另一方面，飞利浦 Brilliance 获得的平均值与西门子 Sensation 和东芝 Aquilion 获得的平均值均相等。在 120kV 下，飞利浦模型获得的尿酸、胱氨酸和鸟粪石的平均 CT 衰减值与西门子和东芝获得的值有显著差异，但与 GE 64 获得的值相等。
根据我们的研究，当直接比较不同品牌和型号的扫描仪时，存在很大的可变性。此外，CT 扫描分析和 HU 评估似乎无法收集足够的信息来描述和识别肾结石的成分。
