西班牙的自愿性食物叶酸强化：使用新的食物叶酸成分数据评估对儿童饮食摄入量的预期贡献。

Voluntary food fortification with folic acid in Spain: predicted contribution to children's dietary intakes as assessed with new food folate composition data.

机构信息

Departamento de Ciencias Farmacéuticas y de la Alimentación, Facultad de Farmacia, Universidad CEU San Pablo, Madrid, Spain.

出版信息

Food Chem. 2013 Oct 1;140(3):526-32. doi: 10.1016/j.foodchem.2013.01.092. Epub 2013 Feb 13.

DOI:10.1016/j.foodchem.2013.01.092

PMID:23601402

Abstract

The Spanish market offers a significant number of folic acid (FA) voluntarily fortified foods. We analysed FA and (6S)-5-methyltetrahydrofolic acid ((6S)-5-CH3-H4PteGlu) content in ready-to-eat cereals (RTEC) (n=68) and cow's milk (n=25) by a previously validated affinity chromatography-HPLC method. Contribution to potential FA intakes for children aged 2-13years, was assessed using food consumption data from a representative nationwide study, folate Recommended Dietary Intakes (RDI), and Upper Levels (UL). Results showed that at all food fortification levels obtained, fortified products provided more than tenfold FA than (6S)-5-CH3-H4PteGlu. For RTEC, the high fortification level provided 6-21%, per serving, of RDI and ⩽32% of ULs at 90th percentile of RTEC consumption (P90). Milk products fortified at the higher level reached on average 54-136% of RDI per serving and only exceeded UL at P90 of milk consumption in children aged 2-5years.

摘要

西班牙市场提供了大量的叶酸（FA）自愿强化食品。我们采用经先前验证的亲和层析-HPLC 方法，分析了即食谷物（RTEC）（n=68）和牛奶（n=25）中的 FA 和（6S）-5-甲基四氢叶酸（（6S）-5-CH3-H4PteGlu）含量。利用全国代表性研究的食物消费数据、叶酸推荐膳食摄入量（RDI）和上限（UL），评估了这些产品对 2-13 岁儿童潜在 FA 摄入量的贡献。结果表明，在所有获得的强化水平下，强化产品提供的 FA 是（6S）-5-CH3-H4PteGlu 的十倍以上。对于 RTEC，高强化水平提供了每份 6-21%的 RDI，以及在 RTEC 消费 90 百分位（P90）时 ⩽32%的 UL（90 百分位时的上限）。强化水平较高的奶制品平均每份提供 54-136%的 RDI，且仅在 2-5 岁儿童的牛奶消费 P90 时超过 UL。