Luo Shun-rong, Zou Liu-he, Yan Chao, Pan Zhi-qiang, Liu Jing-ming, Chen Zhi-yuan, Yin Wei-hong
Beijing Ophthalmol & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100710, China.
Zhonghua Yan Ke Za Zhi. 2013 Jan;49(1):22-6.
Autologous labial salivary gland transplantation has been a promising alternative for the treatment of severe dry eye. In this article, we describe the results of the ocular surface changes after labial salivary gland transplantation and investigate the feasibility of this treatment.
The results of this technique in 8 patients (eyes) who suffered from severe dry eye were prospectively analyzed after surgery (follow-up of 6 months). The best-corrected visual acuity, Schirmer I test, degree of discomfort, usage of pharmaceutical tear substitutes, tear interferometry and slit lamp examination were investigated at different time before and after surgery.
All grafts remained viable and the survival rate is 100%. All patients showed significant increase in the Schirmer's test and they expressed great improvement in their ocular discomfort. The use of artificial tear substitutes was reduced because of the increased ocular surface lubrication.
Although the authors' long-term experience still is limited, we believe that the procedure is a promising alternative approach for severe dry eye.
自体唇腺移植一直是治疗严重干眼症的一种有前景的替代方法。在本文中，我们描述了唇腺移植后眼表变化的结果，并研究了这种治疗方法的可行性。
对8例（眼）严重干眼症患者接受该技术治疗后的结果进行前瞻性分析（术后随访6个月）。在手术前后的不同时间，对最佳矫正视力、泪液分泌试验、不适程度、药用泪液替代品的使用情况、泪液干涉测量和裂隙灯检查进行了研究。
所有移植物均存活，存活率为100%。所有患者的泪液分泌试验均显著增加，眼部不适也有很大改善。由于眼表润滑性增加，人工泪液替代品的使用减少。
尽管作者的长期经验仍然有限，但我们认为该手术是治疗严重干眼症的一种有前景的替代方法。
