先天性心脏病患儿的个性化医疗：从发现到应用

Personalized medicine in the care of the child with congenital heart disease: discovery to application.

作者信息

Binesh Marvasti Tina, D'Alessandro Lisa C A, Manase Dorin, Papaz Tanya, Mital Seema

机构信息

Division of Pediatric Cardiology, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

出版信息

Congenit Heart Dis. 2013 May-Jun;8(3):266-9. doi: 10.1111/chd.12061. Epub 2013 Apr 22.

DOI:10.1111/chd.12061

PMID:23601919

Abstract

On October 27-28, 2012, the SickKids Labatt Family Heart Centre and the Heart Centre Biobank Registry hosted the second international GenomeHeart symposium in Toronto, Ontario. The symposium featured experts in cardiology, developmental biology, pharmacology, genomics, bioinformatics, stem cell biology, biobanking, and ethics. The theme of this year's symposium was the application of emerging technologies in genomics, proteomics, transcriptomics, and bioinformatics to diagnostics and therapeutics of the child with heart disease. Social, ethical, and economic issues were also discussed in the context of clinical translation. We highlight some of the themes that emerged from this exciting 2-day event.

摘要

2012年10月27日至28日，多伦多病童医院拉巴特家庭心脏中心和心脏中心生物样本库登记处，在安大略省多伦多市举办了第二届国际基因组心脏研讨会。该研讨会汇聚了心脏病学、发育生物学、药理学、基因组学、生物信息学、干细胞生物学、生物样本库以及伦理学等领域的专家。今年研讨会的主题是新兴的基因组学、蛋白质组学、转录组学和生物信息学技术在儿童心脏病诊断与治疗中的应用。同时还在临床转化的背景下讨论了社会、伦理和经济问题。我们着重介绍了此次为期两天的精彩活动中出现的一些主题。