Ieiri I, Higuchi S, Nakao Y, Yukawa E, Ohtsubo K, Yoshikawa M, Aoyama T
Department of Hospital Pharmacy, Kyushu University Hospital, Fukuoka, Japan.
DICP. 1990 Jun;24(6):629-32. doi: 10.1177/106002809002400614.
Quantitative evaluation of the therapeutic drug monitoring services (TDMS) provided in Kyushu University Hospital from August 1981 to April 1989 was performed. Since 1982, the annual number of assay requests was about 4300-4400, but the annual number of clinical pharmacokinetic consultation services (CPCS) showed a tendency to increase. Antiepileptics were the drugs for which CPCS were most often performed (26.3 percent of the population given drugs for which TDMS was available); digoxin, lithium, and theophylline followed. Preparation of one consultation required 1.5-2.5 hours. Our TDMS team consists of eight members. In 1988, the average time per week spent for CPCS and TDMS was 8.2 and 11.3 hours per member, respectively. Thus, the number of pharmacists performing CPCS and TDMS was 1.2 and 1.7 full-time equivalents, respectively.
对1981年8月至1989年4月在九州大学医院提供的治疗药物监测服务（TDMS）进行了定量评估。自1982年以来，每年的检测申请数量约为4300 - 4400，但每年的临床药代动力学咨询服务（CPCS）数量呈上升趋势。抗癫痫药是进行CPCS最频繁的药物（在接受TDMS药物治疗的人群中占26.3%）；其次是地高辛、锂和茶碱。一次咨询的准备工作需要1.5 - 2.5小时。我们的TDMS团队由八名成员组成。1988年，每名成员每周用于CPCS和TDMS的平均时间分别为8.2小时和11.3小时。因此，进行CPCS和TDMS的药剂师数量分别相当于1.2名和1.7名全职人员。
