Soltaninejad Kambiz, Nelson Lewis S, Bahreini Seyed Ali, Shadnia Shahin
Department of Forensic Toxicology, Legal Medicine Research Center, Legal Medicine Organization of Iran, Iran.
Indian J Med Sci. 2012 Mar-Apr;66(3-4):66-70.
Aluminum phosphide (AlP) is also known as "rice tablet" in Iran. Due to the high incidence of acute AlP poisoning and its associated mortality in Iran, the authorities banned AlP-containing tablets in 2007. The aim of this study is to evaluate the trend of acute fatal AlP poisoning subsequent to this restriction.
0 This is a retrospective chart review of patients with acute "rice tablet" poisoning who were admitted to Loghman Hakim Hospital Poison Center, Tehran, Iran, from 2007 to 2010. Collected information included gender, age, type of poisoning, marital status, duration of hospitalization, and outcome.
There were 956 cases with a mortality rate of 24.06%. The incidence of fatal AlP poisoning was 2.1 and 5.81 per one million populations of Tehran in 2007 and 2010, respectively. In 223 of the fatal cases (97%) and 697 of the non-fatal cases (96%), the poisoning was intentional. The male to female ratio in the fatal and non-fatal cases was 1.04:1 and 1:1.3, respectively. Most of the fatal cases (n = 122, 53%) were unmarried. The mean age was 27.32 ± 11.31 and 24.5 ± 8.19 years in fatal and non-fatal cases, respectively. In 196 (85.2%) of the fatal cases and in 577 (79%) of non-fatal cases, the duration of hospitalization was less than 24 hours and between 48-72 hours, respectively.
The results of this study showed the incidence of "rice tablet" poisoning, and its mortality increased since 2007 in spite of the ban. It seems that legislative means alone without other interventions, such as suicide prevention and public education, will not always be able to control or prevent acute intentional poisonings.
磷化铝(AlP)在伊朗也被称为“灭鼠药”。由于伊朗急性磷化铝中毒的高发病率及其相关死亡率,当局于2007年禁止了含磷化铝片剂。本研究的目的是评估这一限制措施实施后急性致命磷化铝中毒的趋势。
这是一项对2007年至2010年期间入住伊朗德黑兰洛格曼·哈基姆医院中毒中心的急性“灭鼠药”中毒患者的回顾性病历审查。收集的信息包括性别、年龄、中毒类型、婚姻状况、住院时间和结局。
共有956例病例,死亡率为24.06%。2007年和2010年,德黑兰每百万人口中致命磷化铝中毒的发病率分别为2.1和5.81。在223例致命病例(97%)和697例非致命病例(96%)中,中毒是故意的。致命病例与非致命病例的男女比例分别为1.04:1和1:1.3。大多数致命病例(n = 122,53%)未婚。致命病例和非致命病例的平均年龄分别为27.32±11.31岁和24.5±8.19岁。在196例(85.2%)致命病例和577例(79%)非致命病例中,住院时间分别少于24小时和在48 - 72小时之间。
本研究结果表明,尽管有禁令,但自2007年以来“灭鼠药”中毒的发病率及其死亡率仍有所上升。似乎仅靠立法手段而没有其他干预措施,如预防自杀和公众教育,并不总能控制或预防急性故意中毒。