埃塞俄比亚中北部德布雷塔博尔综合专科医院急诊科收治的成年灭鼠剂中毒患者的灭鼠剂中毒结局及其相关因素
Outcome of Rodenticide Poisoning and Its Associated Factors Among Adult Patients Admitted with Rodenticide Poisoning at the Emergency Unit of Debre Tabor Comprehensive Specialized Hospital, Debre Tabor, North Central Ethiopia.
作者信息
Tassew Sheganew Fetene, Haile Betlhem Amha, Amera Birlie Tekalign
机构信息
Department of Emergency Medicine and Critical Care Nursing, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Department of Human Nutrition, Institute of Public Health, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
出版信息
Open Access Emerg Med. 2023 May 26;15:189-197. doi: 10.2147/OAEM.S405970. eCollection 2023.
INTRODUCTION
Rodenticides are pesticides used to eradicate rodents. It is a common reason for visits to the emergency department and hospitalization, and it is a major public health concern. Intentional or unintentional intoxication can result in severe consequences with a high fatality rate. In Ethiopia, studies on the outcome of rodenticide poisoning are scarce. The goal of this study was to assess the outcomes of rodenticide poisoning and its associated factors in adult patients admitted to the emergency unit of Debre Tabor Comprehensive Specialized Hospital in North Central Ethiopia.
METHODS
A retrospective record review institutional-based cross-sectional study design was used on 156 adult patients treated with rodenticide poisoning at Debre Tabor Comprehensive Specialized Hospital's emergency unit between May 1, 2017 and April 30, 2022. To collect data from patient medical documents and the Health Management Information System, an abstraction sheet was employed. The information was entered into EPI data version 4.6, then exported and analyzed using STATA version 14 software. To analyze the relationship between the dependent and independent variables, bivariable and multivariable regression were used.
RESULTS
A total of 156 participants were involved in the study. The majority of them 55.13% were in the age group of 19-37 years with the median age of 23 years. Three-fourth of the cases were suicidal poisoning. Overall, 49.35% patients presented to Debre Tabor Specialized Hospital had poor outcome. Having suicidal poisoning (AOR = 10.64; 95% CI: 2.43, 46.53), having tachycardia (AOR = 5.41; 95% CI: 1.54, 18.98), being referred from other health center (AOR = 5.78; 95% CI: 1.97, 16.95) were factors associated with poor outcome.
CONCLUSION
Rodenticide poisoning had a poor overall outcome. Suicidal poisoning, tachycardia, and referral from other health facilities were all important predictors in poor rodenticide poisoning outcomes.
引言
灭鼠剂是用于消灭啮齿动物的杀虫剂。它是导致人们前往急诊科就诊和住院的常见原因，也是一个重大的公共卫生问题。有意或无意中毒都可能导致严重后果，死亡率很高。在埃塞俄比亚，关于灭鼠剂中毒后果的研究很少。本研究的目的是评估埃塞俄比亚中北部德布雷塔博尔综合专科医院急诊科收治的成年灭鼠剂中毒患者的中毒后果及其相关因素。
方法
采用回顾性记录 review 基于机构的横断面研究设计，对2017年5月1日至2022年4月30日期间在德布雷塔博尔综合专科医院急诊科接受灭鼠剂中毒治疗的156名成年患者进行研究。为了从患者医疗文件和健康管理信息系统中收集数据，使用了一张摘要表。信息被录入EPI数据4.6版本，然后导出并使用STATA 14软件进行分析。为了分析因变量和自变量之间的关系，使用了双变量和多变量回归。
结果
共有156名参与者参与了本研究。其中大多数人（55.13%）年龄在19至37岁之间，中位年龄为23岁。四分之三的病例为自杀性中毒。总体而言，在德布雷塔博尔专科医院就诊的患者中有49.35%预后不良。自杀性中毒（调整后比值比[AOR]=10.64；95%置信区间[CI]：2.43，46.53）、心动过速（AOR=5.41；95%CI：1.54，18.98）、从其他卫生中心转诊（AOR=5.78；95%CI：1.97，16.95）是与预后不良相关的因素。
结论
灭鼠剂中毒总体预后不良。自杀性中毒、心动过速以及从其他卫生机构转诊都是灭鼠剂中毒预后不良的重要预测因素。
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