Aronson Paul L, Henderson Alicia A, Anupindi Sudha A, Servaes Sabah, Markowitz Richard I, McLoughlin Robert J, Woodford Ashley L, Mistry Rakesh D
Department of Pediatrics, Section of Emergency Medicine, Yale School of Medicine, New Haven, CT 06511, USA.
Pediatr Emerg Care. 2013 May;29(5):584-7. doi: 10.1097/PEC.0b013e31828e62d6.
The objectives of this study were to determine agreement of abdominal radiography (AXR) interpretation and to compare test characteristics, between pediatric emergency medicine (PEM) physicians and pediatric radiologists for evaluation of intussusception.
This was a retrospective cohort study of children aged 3 months to 3 years presenting to a pediatric emergency department (ED) between 2007 and 2009. For inclusion, subjects required an ED presentation for suspected intussusception, performance of a 2-view AXR (supine and upright/lateral decubitus views) and abdominal ultrasound performed during the ED visit, and a subsequent criterion-standard measure for intussusception available (contrast enema, operative report, or clinical follow-up). All AXRs were reviewed by 2 blinded PEM physicians and 2 pediatric radiologists. Interrater agreement (κ) for AXR interpretation and diagnostic test characteristics were calculated for comparison.
A total of 286 children were included; intussusception was present in 61 patients (21.3%). Moderate agreement was present between the PEM physicians and radiologists for AXR assessment, with κ = 0.57 (95% confidence interval [CI], 0.47-0.66). Radiologist AXR interpretation had specificity of 86.7% (95% CI, 81.6-90.5), sensitivity of 62.3% (95% CI, 49.8-73.4), positive predictive value of 55.9% (95% CI, 43.3-67.9), and negative predictive value of 89.4% (95% CI, 84.6-93.2). Pediatric emergency medicine physician AXR interpretation had specificity of 68.9% (95% CI, 62.6-74.6), sensitivity of 78.7% (95% CI, 66.9-87.1), positive predictive value of 40.7% (95% CI, 32.2-49.7), and negative predictive value of 92.3% (95% CI, 87.1-95.5).
Agreement between PEM physicians and pediatric radiologists for evaluation of AXR in suspected intussusception is moderate. Sensitivity and negative predictive value of AXR alone are not sufficiently high overall to exclude intussusception; however, PEM physician interpretation of AXR may possess utility in determining need for abdominal ultrasound in low-risk patients given the high negative predictive value.
本研究的目的是确定腹部X线摄影(AXR)解读的一致性,并比较儿科急诊医学(PEM)医生和儿科放射科医生在评估肠套叠时的检查特征。
这是一项对2007年至2009年期间到儿科急诊科(ED)就诊的3个月至3岁儿童进行的回顾性队列研究。纳入标准为:因疑似肠套叠到急诊科就诊、在急诊科就诊期间进行了双视图AXR(仰卧位和直立/侧卧位)和腹部超声检查,且有后续可用的肠套叠标准测量方法(造影灌肠、手术报告或临床随访)。所有AXR均由2名不知情的PEM医生和2名儿科放射科医生进行审查。计算AXR解读的评分者间一致性(κ)和诊断检查特征以进行比较。
共纳入286名儿童;61名患者(21.3%)存在肠套叠。PEM医生和放射科医生在AXR评估方面存在中度一致性,κ = 0.57(95%置信区间[CI],0.47 - 0.66)。放射科医生对AXR的解读特异性为86.7%(95% CI,81.6 - 90.5),敏感性为62.3%(95% CI,49.8 - 73.4),阳性预测值为55.9%(95% CI,43.3 - 67.9),阴性预测值为89.4%(95% CI,84.6 - 93.2)。儿科急诊医学医生对AXR的解读特异性为68.9%(95% CI,62.6 - 74.6),敏感性为78.7%(95% CI,66.9 - 87.1),阳性预测值为40.7%(95% CI,3