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德国 Hodgkin 淋巴瘤循证指南。放疗科医生关注的问题。

The German evidence-based guidelines for Hodgkin's lymphoma. Aspects for radiation oncologists.

机构信息

Department of Radiation Oncology, University of Muenster, Albert-Schweitzer-Campus 1, Münster, Germany.

出版信息

Strahlenther Onkol. 2013 Jun;189(6):445-7. doi: 10.1007/s00066-013-0331-4. Epub 2013 Apr 21.

DOI:10.1007/s00066-013-0331-4
PMID:23604187
Abstract

This report reviews aspects of the German evidence-based guidelines for Hodgkin's lymphoma relevant to radiation oncologists. Stage-adapted treatment is discussed with the focus on radiotherapy. Up-to-date literature citations provide an overview of current recommendations.

摘要

本报告回顾了德国霍奇金淋巴瘤循证指南中与放射肿瘤学家相关的方面。讨论了基于分期的治疗方法，重点是放射治疗。最新的文献引用提供了当前建议的概述。

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1
The German evidence-based guidelines for Hodgkin's lymphoma. Aspects for radiation oncologists.德国 Hodgkin 淋巴瘤循证指南。放疗科医生关注的问题。
Strahlenther Onkol. 2013 Jun;189(6):445-7. doi: 10.1007/s00066-013-0331-4. Epub 2013 Apr 21.
2
Importance of F18-fluorodeoxy-D-2-glucose positron emission tomography (FDG-PET) for staging and therapy control of Hodgkin's lymphoma in childhood and adolescence - consequences for the GPOH-HD 2003 protocol.18F-氟脱氧-D-2-葡萄糖正电子发射断层扫描（FDG-PET）在儿童和青少年霍奇金淋巴瘤分期及治疗监测中的重要性——对GPOH-HD 2003方案的影响
Onkologie. 2003 Oct;26(5):489-93. doi: 10.1159/000072984.
3
Whole-body positron emission tomography using 18F-fluorodeoxyglucose for posttreatment evaluation in Hodgkin's disease and non-Hodgkin's lymphoma has higher diagnostic and prognostic value than classical computed tomography scan imaging.使用18F-氟脱氧葡萄糖的全身正电子发射断层扫描在霍奇金淋巴瘤和非霍奇金淋巴瘤的治疗后评估中比传统计算机断层扫描成像具有更高的诊断和预后价值。
Blood. 1999 Jul 15;94(2):429-33.
4
Clinical relevance of positron emission tomography (PET) in treatment control and relapse of Hodgkin's disease.
Strahlenther Onkol. 2001 Mar;177(3):138-44. doi: 10.1007/pl00002394.
5
Relapse analysis of irradiated patients within the HD15 trial of the German Hodgkin Study Group.德国霍奇金淋巴瘤研究组HD15试验中接受放疗患者的复发分析。
Int J Radiat Oncol Biol Phys. 2015 May 1;92(1):46-53. doi: 10.1016/j.ijrobp.2015.01.048.
6
[Therapy of Hodgkin lymphoma: chances of remission are good, treatment tolerance needs improvement].[霍奇金淋巴瘤的治疗：缓解机会良好，治疗耐受性有待提高]
MMW Fortschr Med. 2011 Oct 13;153(41):17. doi: 10.1007/BF03368883.
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Combination chemoradiotherapy in early Hodgkin lymphoma.早期霍奇金淋巴瘤的联合化放疗。
Hematol Oncol Clin North Am. 2014 Feb;28(1):33-47. doi: 10.1016/j.hoc.2013.10.010.
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A Contribution to solve the problem of the need for consolidative radiotherapy after intensive chemotherapy in advanced stages of Hodgkin's lymphoma--analysis of a quality control program initiated by the radiotherapy reference center of the German Hodgkin Study Group (GHSG).对解决晚期霍奇金淋巴瘤强化化疗后巩固性放疗必要性问题的一项贡献——德国霍奇金淋巴瘤研究组（GHSG）放疗参考中心启动的质量控制项目分析
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Does Radiation Have a Role in Advanced Stage Hodgkin's or Non-Hodgkin Lymphoma?放射治疗在晚期霍奇金淋巴瘤或非霍奇金淋巴瘤中起作用吗？
Curr Treat Options Oncol. 2016 Jan;17(1):4. doi: 10.1007/s11864-015-0377-x.
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[Role of FDG-PET in Staging and Therapy of Children with Hodgkin Lymphoma].[氟代脱氧葡萄糖正电子发射断层扫描在儿童霍奇金淋巴瘤分期及治疗中的作用]
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Checkpoint inhibitors and radiation treatment in Hodgkin's lymphoma : New study concepts of the German Hodgkin Study Group.霍奇金淋巴瘤中的检查点抑制剂与放射治疗：德国霍奇金淋巴瘤研究组的新研究概念
Strahlenther Onkol. 2017 Feb;193(2):95-99. doi: 10.1007/s00066-016-1050-4. Epub 2016 Oct 4.
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Radiation-induced camptocormia and dropped head syndrome: Review and case report of radiation-induced movement disorders.放射性脊髓病和垂头综合征：放射性运动障碍的综述与病例报告
Strahlenther Onkol. 2015 Oct;191(10):765-70. doi: 10.1007/s00066-015-0857-8. Epub 2015 Jun 14.
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Breath-hold technique in conventional APPA or intensity-modulated radiotherapy for Hodgkin's lymphoma: Comparison of ILROG IS-RT and the GHSG IF-RT.

本文引用的文献

1
Randomized phase III trial of ABVD versus Stanford V with or without radiation therapy in locally extensive and advanced-stage Hodgkin lymphoma: an intergroup study coordinated by the Eastern Cooperative Oncology Group (E2496).ABVD 方案与 Stanford V 方案联合或不联合放疗治疗局部广泛期和晚期霍奇金淋巴瘤的随机 III 期临床试验：东部肿瘤协作组（E2496）协调的一项多中心研究。
J Clin Oncol. 2013 Feb 20;31(6):684-91. doi: 10.1200/JCO.2012.43.4803. Epub 2012 Nov 26.
2
Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial.强化化疗联合 PET 引导放疗与单纯强化化疗治疗晚期霍奇金淋巴瘤（HD15 试验）：一项随机、开放标签、III 期非劣效性试验。
Lancet. 2012 May 12;379(9828):1791-9. doi: 10.1016/S0140-6736(11)61940-5. Epub 2012 Apr 4.
3
霍奇金淋巴瘤常规加速部分乳腺照射（APPA）或调强放疗中的屏气技术：国际淋巴瘤放射肿瘤学组（ILROG）IS-RT与德国霍奇金淋巴瘤研究组（GHSG）IF-RT的比较
Strahlenther Onkol. 2015 Sep;191(9):717-25. doi: 10.1007/s00066-015-0839-x. Epub 2015 Apr 16.
4
Primary EBV-positive Hodgkin's lymphoma of the CNS under azathioprine treatment: case report and review of the literature.接受硫唑嘌呤治疗的中枢神经系统原发性EB病毒阳性霍奇金淋巴瘤：病例报告及文献复习
Strahlenther Onkol. 2014 Sep;190(9):847-52. doi: 10.1007/s00066-014-0670-9. Epub 2014 May 14.
5
Schedule-dependent interaction between vinblastine and irradiation in experimental sarcoma.长春新碱与放疗在实验性肉瘤中时相依赖性相互作用。
Strahlenther Onkol. 2014 Jul;190(7):661-6. doi: 10.1007/s00066-014-0645-x. Epub 2014 Mar 11.
Dose-intensification in early unfavorable Hodgkin's lymphoma: final analysis of the German Hodgkin Study Group HD14 trial.早期预后不良型霍奇金淋巴瘤的剂量强化治疗：德国霍奇金研究组 HD14 试验的最终分析。
J Clin Oncol. 2012 Mar 20;30(9):907-13. doi: 10.1200/JCO.2011.38.5807. Epub 2012 Jan 23.
4
Eight cycles of escalated-dose BEACOPP compared with four cycles of escalated-dose BEACOPP followed by four cycles of baseline-dose BEACOPP with or without radiotherapy in patients with advanced-stage hodgkin's lymphoma: final analysis of the HD12 trial of the German Hodgkin Study Group.与 4 个周期递增剂量 BEACOPP 序贯 4 个周期标准剂量 BEACOPP 联合或不联合放疗相比，8 个周期递增剂量 BEACOPP 治疗晚期霍奇金淋巴瘤患者：德国霍奇金研究组 HD12 试验的最终分析。
J Clin Oncol. 2011 Nov 10;29(32):4234-42. doi: 10.1200/JCO.2010.33.9549. Epub 2011 Oct 11.
5
Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma.早期霍奇金淋巴瘤患者的治疗强度降低。
N Engl J Med. 2010 Aug 12;363(7):640-52. doi: 10.1056/NEJMoa1000067.
6
Intensified chemotherapy and dose-reduced involved-field radiotherapy in patients with early unfavorable Hodgkin's lymphoma: final analysis of the German Hodgkin Study Group HD11 trial.强化化疗联合受累野剂量降低放疗治疗早期不良预后霍奇金淋巴瘤患者：德国霍奇金研究组 HD11 试验的最终分析。
J Clin Oncol. 2010 Sep 20;28(27):4199-206. doi: 10.1200/JCO.2010.29.8018. Epub 2010 Aug 16.
7
Prognostic significance of mid- and post-ABVD PET imaging in Hodgkin's lymphoma: the importance of involved-field radiotherapy.ABVD 后中期 PET 成像对霍奇金淋巴瘤预后的意义：累及野放疗的重要性。
Ann Oncol. 2009 Nov;20(11):1848-53. doi: 10.1093/annonc/mdp071. Epub 2009 Jun 18.
8
Fluorine-18-fluorodeoxyglucose positron emission tomography for interim response assessment of advanced-stage Hodgkin's lymphoma and diffuse large B-cell lymphoma: a systematic review.氟-18-氟脱氧葡萄糖正电子发射断层扫描用于晚期霍奇金淋巴瘤和弥漫性大B细胞淋巴瘤的中期疗效评估：一项系统评价
J Clin Oncol. 2009 Apr 10;27(11):1906-14. doi: 10.1200/JCO.2008.16.0861. Epub 2009 Mar 9.
9
Involved-node radiotherapy in early-stage Hodgkin's lymphoma. Definition and guidelines of the German Hodgkin Study Group (GHSG).早期霍奇金淋巴瘤的受累淋巴结放疗。德国霍奇金淋巴瘤研究组（GHSG）的定义与指南
Strahlenther Onkol. 2008 Aug;184(8):406-10. doi: 10.1007/s00066-008-1882-7.
10
Positron emission tomography has a high negative predictive value for progression or early relapse for patients with residual disease after first-line chemotherapy in advanced-stage Hodgkin lymphoma.正电子发射断层扫描对于晚期霍奇金淋巴瘤一线化疗后有残留病灶的患者疾病进展或早期复发具有较高的阴性预测价值。
Blood. 2008 Nov 15;112(10):3989-94. doi: 10.1182/blood-2008-06-155820. Epub 2008 Aug 29.