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Growth hormone in health and disease: Biological markers of tissue-specific effects of GH therapy.

作者信息

Rogol Alan D

出版信息

Nat Rev Endocrinol. 2013 Jun;9(6):318-20. doi: 10.1038/nrendo.2013.80. Epub 2013 Apr 23.

DOI:10.1038/nrendo.2013.80
PMID:23609337
Abstract
摘要

相似文献

1
Growth hormone in health and disease: Biological markers of tissue-specific effects of GH therapy.健康与疾病中的生长激素：生长激素疗法组织特异性效应的生物标志物
Nat Rev Endocrinol. 2013 Jun;9(6):318-20. doi: 10.1038/nrendo.2013.80. Epub 2013 Apr 23.
2
Protein markers predict body composition during growth hormone treatment in short prepubertal children.蛋白质标志物可预测青春期前儿童生长激素治疗期间的身体成分变化。
Clin Endocrinol (Oxf). 2013 Nov;79(5):675-82. doi: 10.1111/cen.12196. Epub 2013 Apr 11.
3
Growth hormone decreases visceral fat and improves cardiovascular risk markers in women with hypopituitarism: a randomized, placebo-controlled study.生长激素可减少垂体功能减退女性的内脏脂肪并改善心血管风险指标：一项随机、安慰剂对照研究。
J Clin Endocrinol Metab. 2008 Jun;93(6):2063-71. doi: 10.1210/jc.2007-2371. Epub 2008 Apr 1.
4
Effects of growth hormone replacement therapy on lipids, lipoproteins and apolipoproteins: is the increased apolipoprotein A-1/B ratio the only benefit?
Pediatr Int. 2000 Apr;42(2):151-4. doi: 10.1046/j.1442-200x.2000.01193.x.
5
The favourable effects of growth hormone (GH) substitution on hypercholesterolaemia in GH-deficient adults are not associated with concomitant reductions in adiposity. A 12 month placebo-controlled study.生长激素（GH）替代治疗对生长激素缺乏的成年人高胆固醇血症的有益作用与体脂率的同时降低无关。一项为期12个月的安慰剂对照研究。
Int J Obes Relat Metab Disord. 1998 Jun;22(6):529-36. doi: 10.1038/sj.ijo.0800618.
6
Increase of serum lipoprotein (a) levels during growth hormone therapy in normal short children.正常身材矮小儿童生长激素治疗期间血清脂蛋白(a)水平升高
Eur J Pediatr. 1998 Jan;157(1):4-7. doi: 10.1007/s004310050756.
7
Plasma cholesteryl ester transfer protein and lipoprotein levels during treatment of growth hormone-deficient adult humans.生长激素缺乏的成年人类治疗期间的血浆胆固醇酯转运蛋白和脂蛋白水平
Lipids. 2001 Jun;36(6):549-54. doi: 10.1007/s11745-001-0756-y.
8
Growth hormone (GH)-deficient men are more responsive to GH replacement therapy than women.生长激素（GH）缺乏的男性对生长激素替代疗法的反应比女性更敏感。
J Clin Endocrinol Metab. 1997 Feb;82(2):550-5. doi: 10.1210/jcem.82.2.3776.
9
A nine-month, placebo-controlled study of the effects of growth hormone treatment on lipoproteins and LDL size in abdominally obese men.一项为期九个月、以安慰剂为对照的研究，旨在探究生长激素治疗对腹部肥胖男性脂蛋白及低密度脂蛋白大小的影响。
Growth Horm IGF Res. 2000 Jun;10(3):118-26. doi: 10.1054/ghir.2000.0148.
10
Commencing growth hormone replacement in adults with a fixed low dose. Effects on serum lipoproteins, glucose metabolism, body composition, and cardiovascular function.以固定低剂量开始对成人进行生长激素替代治疗。对血清脂蛋白、葡萄糖代谢、身体成分和心血管功能的影响。
Growth Horm IGF Res. 2001 Oct;11(5):273-81. doi: 10.1054/ghir.2001.0240.

本文引用的文献

1
Protein markers predict body composition during growth hormone treatment in short prepubertal children.蛋白质标志物可预测青春期前儿童生长激素治疗期间的身体成分变化。
Clin Endocrinol (Oxf). 2013 Nov;79(5):675-82. doi: 10.1111/cen.12196. Epub 2013 Apr 11.
2
Fifteen years of GH replacement improves body composition and cardiovascular risk factors.15 年的 GH 替代治疗可改善身体成分和心血管危险因素。
Eur J Endocrinol. 2013 Apr 15;168(5):745-53. doi: 10.1530/EJE-12-1083. Print 2013 May.
3
Overall and cause-specific mortality in GH-deficient adults on GH replacement.
生长激素缺乏症成人接受生长激素替代治疗后的总体死亡率和死因特异性死亡率。
Eur J Endocrinol. 2012 Jun;166(6):1069-77. doi: 10.1530/EJE-11-1028. Epub 2012 Mar 28.
4
Effects of recombinant human growth hormone therapy in adults with Prader-Willi syndrome: a meta-analysis.生长激素治疗 Prader-Willi 综合征成人患者的效果：一项荟萃分析。
Clin Endocrinol (Oxf). 2012 Jul;77(1):86-93. doi: 10.1111/j.1365-2265.2011.04303.x.
5
Proteins related to lipoprotein profile were identified using a pharmaco-proteomic approach as markers for growth response to growth hormone (GH) treatment in short prepubertal children.采用药物蛋白质组学方法鉴定了与脂蛋白谱相关的蛋白质，作为青春期前矮小儿童对生长激素（GH）治疗生长反应的标志物。
Proteome Sci. 2009 Nov 2;7:40. doi: 10.1186/1477-5956-7-40.
6
Alterations in body composition and fat distribution in growth hormone-deficient prepubertal children during growth hormone therapy.生长激素治疗期间生长激素缺乏的青春期前儿童身体成分和脂肪分布的变化。
Metabolism. 2001 May;50(5):537-47. doi: 10.1053/meta.2001.22510.
7
The effects of 10 years of recombinant human growth hormone (GH) in adult GH-deficient patients.十年重组人生长激素（GH）对成年生长激素缺乏患者的影响。
J Clin Endocrinol Metab. 1999 Aug;84(8):2596-602. doi: 10.1210/jcem.84.8.5916.