Romero López J, Sarasa Corral J L, Yáñez Baña R M, Pareja Grande J A, González-Elipe J
Servicio de Neurología, Fundación Jiménez Díaz, Universidad Autónoma de Madrid.
Neurologia. 1990 Mar;5(3):98-101.
Granulomatous angiitis of the central nervous system is an uncommon condition characterized by vascular wall necrosis, inflammatory exudate and development of giant cells in medium and small size vessels. The pathogenesis of this disease remains unknown, but it has been associated with immune complexes, mechanical factors and infection by the varicella-zoster virus. We report a young patient who presented with herpes zoster involving the VII cranial nerve and contralateral hemiplegia. Subsequently, pontine infarct and fatal subarachnoid hemorrhage developed. The pathological study showed granulomatous angiitis of basilar artery.
中枢神经系统肉芽肿性血管炎是一种罕见的疾病,其特征为血管壁坏死、炎性渗出以及中小血管中出现巨细胞。该疾病的发病机制尚不清楚,但已发现其与免疫复合物、机械因素以及水痘-带状疱疹病毒感染有关。我们报告了一名年轻患者,其表现为累及面神经的带状疱疹及对侧偏瘫。随后,出现了脑桥梗死和致命性蛛网膜下腔出血。病理研究显示基底动脉肉芽肿性血管炎。