Department of Bioengineering, Imperial College London, B304b Bessemer Building, London, SW7 2AZ, UK.
Ann Biomed Eng. 2013 Sep;41(9):1957-67. doi: 10.1007/s10439-013-0814-6. Epub 2013 Apr 24.
Current military conflicts are characterized by the use of the improvised explosive device. Improvements in personal protection, medical care, and evacuation logistics have resulted in increasing numbers of casualties surviving with complex musculoskeletal injuries, often leading to life-long disability. Thus, there exists an urgent requirement to investigate the mechanism of extremity injury caused by these devices in order to develop mitigation strategies. In addition, the wounds of war are no longer restricted to the battlefield; similar injuries can be witnessed in civilian centers following a terrorist attack. Key to understanding such mechanisms of injury is the ability to deconstruct the complexities of an explosive event into a controlled, laboratory-based environment. In this article, a traumatic injury simulator, designed to recreate in the laboratory the impulse that is transferred to the lower extremity from an anti-vehicle explosion, is presented and characterized experimentally and numerically. Tests with instrumented cadaveric limbs were then conducted to assess the simulator's ability to interact with the human in two mounting conditions, simulating typical seated and standing vehicle passengers. This experimental device will now allow us to (a) gain comprehensive understanding of the load-transfer mechanisms through the lower limb, (b) characterize the dissipating capacity of mitigation technologies, and (c) assess the bio-fidelity of surrogates.
当前的军事冲突以简易爆炸装置的使用为特征。由于个人防护、医疗和后送后勤方面的改进,越来越多的伤员在遭受复杂的肌肉骨骼损伤后幸存下来,但往往导致终身残疾。因此,迫切需要研究这些装置造成的四肢损伤的机制,以制定缓解策略。此外,战争的创伤不再局限于战场;在恐怖袭击后,在民用中心也可以看到类似的伤害。了解此类损伤机制的关键是能够将爆炸事件的复杂性分解为一个受控的、基于实验室的环境。本文提出并实验和数值上表征了一种创伤模拟器,旨在实验室重现从反车辆爆炸传递到下肢的脉冲。然后,对装有仪器的尸体肢体进行了测试,以评估该模拟器在模拟典型的坐式和站立式车辆乘客的两种安装条件下与人体相互作用的能力。这种实验设备将使我们能够:(a)全面了解通过下肢的负载传递机制;(b)描述缓解技术的耗散能力;(c)评估替代物的生物逼真度。