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遥测脑电图与大鼠：神经科学家指南

Telemetric EEG and the rat: a guide for neuroscientists.

作者信息

Abdullah Jafri Malin, Rafiqul Islam Mohammad

机构信息

Malaysian Journal of Medical Sciences, Universiti Sains Malaysia Press, Universiti Sains Malaysia Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.

出版信息

Malays J Med Sci. 2012 Oct;19(4):1-5.

PMID:23613643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3629674/
Abstract

Telemetric EEG in the rat's brain has been used for experiments which tests the effects of an antiepileptic compound on it's antiseizures activity. A simple classification correlating epileptiform discharge and Racine's behavioral activity is discussed.

摘要

大鼠大脑的遥测脑电图已被用于测试抗癫痫化合物对其抗癫痫活性影响的实验。本文讨论了一种将癫痫样放电与拉辛行为活动相关联的简单分类方法。

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本文引用的文献

1
Key factors in the discovery and development of new antiepileptic drugs.新型抗癫痫药物研发的关键因素。
Nat Rev Drug Discov. 2010 Jan;9(1):68-82. doi: 10.1038/nrd2997.
2
EEG spike activity precedes epilepsy after kainate-induced status epilepticus.红藻氨酸诱导癫痫持续状态后，脑电图尖峰活动先于癫痫发作。
Epilepsia. 2010 Mar;51(3):371-83. doi: 10.1111/j.1528-1167.2009.02339.x. Epub 2009 Oct 20.
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Public statement: guidelines for the assessment and management of pain in rodents and rabbits.公开声明：啮齿动物和兔子疼痛评估与管理指南
J Am Assoc Lab Anim Sci. 2007 Mar;46(2):97-108.
4
Efficient unsupervised algorithms for the detection of seizures in continuous EEG recordings from rats after brain injury.用于检测脑损伤大鼠连续脑电图记录中癫痫发作的高效无监督算法。
J Neurosci Methods. 2006 Apr 15;152(1-2):255-66. doi: 10.1016/j.jneumeth.2005.09.014. Epub 2005 Dec 5.
5
Chronic levetiracetam treatment early in life decreases epileptiform events in young GAERS, but does not prevent the expression of spike and wave discharges during adulthood.在幼年GAERS中，早期长期使用左乙拉西坦治疗可减少癫痫样发作，但不能预防成年期棘波和慢波放电的出现。
Seizure. 2005 Sep;14(6):403-11. doi: 10.1016/j.seizure.2005.07.001.
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Pathophysiological mechanisms of genetic absence epilepsy in the rat.大鼠遗传性失神癫痫的病理生理机制
Prog Neurobiol. 1998 May;55(1):27-57. doi: 10.1016/s0301-0082(97)00091-9.
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Modification of seizure activity by electrical stimulation. I. After-discharge threshold.
Electroencephalogr Clin Neurophysiol. 1972 Mar;32(3):269-79. doi: 10.1016/0013-4694(72)90176-9.
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Genetic absence epilepsy in rats from Strasbourg--a review.斯特拉斯堡大鼠遗传性失神癫痫——综述
J Neural Transm Suppl. 1992;35:37-69. doi: 10.1007/978-3-7091-9206-1_4.