Sahmyook Medical Center Seoul Hospital, Seoul, Korea.
Korean Circ J. 2013 Mar;43(3):204-6. doi: 10.4070/kcj.2013.43.3.204. Epub 2013 Mar 31.
Myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) is a multisystem clinical syndrome manifested by mitochondrial myopathy, encephalopathy, lactic acidosis and recurrent stroke-like episodes. A 27-year-old female with MELAS syndrome presented with cerebral infarction. Echocardiography revealed a thrombus attached to the apex of the hypertrophied left ventricle, with decreased systolic function. The embolism of the intracardiac thrombus might have been the cause of stroke. There should be more consideration given to the increased possibility of intracardiac thrombus formation when a MELAS patient with cardiac involvement is encountered.
线粒体脑肌病伴高乳酸血症和卒中样发作综合征(MELAS)是一种多系统临床综合征,表现为线粒体肌病、脑病、乳酸酸中毒和反复发作的类似中风样发作。一位 27 岁的女性患有 MELAS 综合征,表现为脑梗死。超声心动图显示左心室肥厚心尖附着血栓,收缩功能下降。心腔内血栓栓塞可能是中风的原因。当遇到伴有心脏受累的 MELAS 患者时,应更多考虑心腔内血栓形成的可能性增加。