Christie P M, Hill G L
University Department of Surgery, Auckland Hospital, New Zealand.
Dis Colon Rectum. 1990 Jul;33(7):584-6. doi: 10.1007/BF02052211.
In 16 patients with ulcerative colitis, total body fat, total body protein, and total body water were measured before and two weeks, three months, and twelve months after the establishment of an ileoanal J-pouch anastomosis. The 16 patients underwent elective surgery for their inflammatory bowel disease but were significantly protein depleted before surgery when their body composition was first measured. Twelve months later, all patients were in good health, back to work, and had normally functioning pouches (average stool frequency 4.3 +/- 1.4 per day). As a group, their stores of body protein and hydration state had returned to normal limits although their body fat stores were increased. Over the postoperative period there were significant losses of weight, protein, fat, fat-free mass, and total body water. These levels had returned to preoperative values (but not to normal) three months later. It is concluded that protein depleted patients with ulcerative colitis presenting for major surgery continue to have distorted body composition for several months after surgery but after approximately 12 months, when they have returned to work and feel well, body composition has returned to normal.
对16例溃疡性结肠炎患者在回肠肛管J形贮袋吻合术建立前以及建立后的两周、三个月和十二个月测量了全身脂肪、全身蛋白质和全身水含量。这16例患者因炎症性肠病接受了择期手术，但在首次测量身体成分时，术前蛋白质严重缺乏。十二个月后，所有患者身体健康，恢复工作，贮袋功能正常（平均每日排便频率4.3±1.4次）。作为一个群体，他们的身体蛋白质储备和水合状态已恢复到正常范围，尽管他们的身体脂肪储备有所增加。术后期间，体重、蛋白质、脂肪、去脂体重和全身水含量均有显著下降。三个月后这些水平恢复到术前值（但未恢复正常）。得出的结论是，因溃疡性结肠炎而蛋白质缺乏并接受大手术的患者，术后数月身体成分仍持续异常，但大约12个月后，当他们恢复工作且感觉良好时，身体成分已恢复正常。
