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[沙利度胺诱导胚胎病中的骶前脑脊膜膨出]

[Presacral meningocele in thalidomide-induced embryopathy].

作者信息

Bröcheler J, Halfmann R

机构信息

Neurochirurgische Klinik, Rheinisch-Westfälische Technische Hochschule Aachen.

出版信息

Dtsch Med Wochenschr. 1990 Jun 22;115(25):977-9. doi: 10.1055/s-2008-1065108.

Abstract

A now 27-year-old man, known to have a thalidomide embryopathy with multiple malformations, including a sacral deformity, developed in the course of a few weeks a disorder of bladder emptying, colicky lower abdominal pain and, finally, abnormal stools. Exploratory laparotomy revealed an anterior sacral meningocele, confirmed by computed tomography with intrathecal contrast medium injection. After surgical removal of the meningocele all bladder and rectal disorders disappeared. The course of the disease and the radiological findings are typical of a space-occupying anterior sacral meningocele.

摘要

一名现年27岁的男子,已知患有沙利度胺胚胎病并伴有多种畸形,包括骶骨畸形,在几周内出现了膀胱排空障碍、下腹部绞痛,最终出现大便异常。剖腹探查发现一个骶前脊膜膨出,经鞘内注射造影剂的计算机断层扫描得以证实。手术切除脊膜膨出后,所有膀胱和直肠疾病均消失。该疾病的病程和影像学表现是典型的占位性骶前脊膜膨出。

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