Readford P K, Lester G D, Secombe C J
The Equine Centre, School of Veterinary and Biomedical Sciences, Murdoch University, Western Australia, Australia.
Aust Vet J. 2013 May;91(5):209-12. doi: 10.1111/avj.12039. Epub 2013 Mar 11.
Two cases of temporohyoid osteoarthropathy (THO) in young Australian horses are described. The pathogenesis of THO is yet to be fully elucidated, but current theories include extension of infection from otitis media or interna to the temporohyoid joint or a primary but non-infectious degenerative condition within the temporohyoid joint. The young age of the horses and the unilateral distribution suggested an infectious aetiology. Both horses partially responded to treatment with broad-spectrum antimicrobial and anti-inflammatory drugs with concurrent management of ulcerative keratitis. The management of violent head shaking in one horse included the administration of gabapentin, an anticonvulsant known to have antihyperalgesic effects and reduce neuropathic pain.
本文描述了两例澳大利亚幼马颞骨-舌骨骨关节炎(THO)病例。THO的发病机制尚未完全阐明,但目前的理论包括感染从中耳炎或内耳炎蔓延至颞骨-舌骨关节,或颞骨-舌骨关节内的原发性非感染性退行性病变。马匹的年轻年龄和单侧分布提示病因具有感染性。两匹马对广谱抗菌和抗炎药物治疗以及同时对溃疡性角膜炎的处理均有部分反应。对其中一匹马剧烈摇头的处理包括给予加巴喷丁,这是一种已知具有抗痛觉过敏作用并能减轻神经性疼痛的抗惊厥药。