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酒精饮料作为原发性头痛的触发因素。

Alcoholic drinks as triggers in primary headaches.

机构信息

Headache Centre, Department of Neurology, San Giuseppe Hospital, Empoli, FI, Italy.

出版信息

Pain Med. 2013 Aug;14(8):1254-9. doi: 10.1111/pme.12127. Epub 2013 Apr 24.

Abstract

OBJECTIVE

This project aims to investigate the role of alcoholic drinks (ADs) as triggers for primary headaches.

METHODS

Patients followed in the Headache Centre and presenting with migraine without aura, migraine with aura (MA), chronic migraine (CM), and tension-type headache (TH) were asked if their headache was precipitated by AD and also about their alcohol habits. Individual characteristics and drink habits were evaluated within two binary logistic models.

RESULTS

About one half (49.7%) of patients were abstainers, 17.6% were habitual consumers, and 32.5% were occasional consumers. Out of 448 patients, only 22 (4.9%), all with migraine, reported AD as a trigger factor. None of 44 patients with MA and none of 47 patients with TH reported AD as a trigger factor. Among those patients with migraine who consume AD, only 8% reported that AD can precipitate their headache. Multivariate analyses showed that AD use, both occasional and habitual, is unrelated to TH. Moreover, analysis performed among migraine patients, points out that occasional and habitual drinkers have a lower risk of presenting with CM than abstainers, although statistical significance occurred only among occasional drinkers. Only 3% of migraine patients who abstain from AD reported that they do not consume alcohol because it triggers their headache.

CONCLUSION

Our study shows that AD acts as headache triggers in a small percentage of migraine patients. Differing from some prior studies, our data suggest that AD do not trigger MA and TH attacks. Moreover, the percentage of abstainers in our sample is higher compared with that reported in general population surveys.

摘要

目的

本项目旨在研究酒精饮料(AD)作为原发性头痛诱因的作用。

方法

在头痛中心就诊并表现为无先兆偏头痛、有先兆偏头痛(MA)、慢性偏头痛(CM)和紧张型头痛(TH)的患者,被询问他们的头痛是否由 AD 引发,以及他们的饮酒习惯。在两个二项逻辑回归模型中评估个体特征和饮酒习惯。

结果

约一半(49.7%)的患者为戒酒者,17.6%为习惯性饮酒者,32.5%为偶尔饮酒者。在 448 名患者中,只有 22 名(4.9%),均为偏头痛患者,报告 AD 是触发因素。无 MA 患者(44 名)和 TH 患者(47 名)报告 AD 为触发因素。在那些饮用 AD 的偏头痛患者中,只有 8%的患者报告 AD 可引发头痛。多变量分析表明,偶尔和习惯性饮酒与 TH 无关。此外,在偏头痛患者中的分析表明,偶尔饮酒者和习惯性饮酒者比戒酒者发生 CM 的风险较低,尽管仅在偶尔饮酒者中具有统计学意义。只有 3%的戒酒偏头痛患者报告说他们不饮酒是因为 AD 会引发头痛。

结论

我们的研究表明,AD 在一小部分偏头痛患者中作为头痛的诱因。与一些先前的研究不同,我们的数据表明 AD 不会引发 MA 和 TH 发作。此外,与一般人群调查相比,我们样本中的戒酒者比例较高。

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