Bayraktar M, Ergin M, Boyacioglu A, Demir S
Department of Endocrinology, Hacettepe University School of Medicine, Ankara, Turkey.
J Int Med Res. 1990 May-Jun;18(3):253-5. doi: 10.1177/030006059001800312.
To demonstrate whether or not fine needle aspiration biopsy caused release of thyroglobulin into the circulation and if there was a correlation between histological diagnosis and thyroglobulin release from thyroid during aspiration, serum thyroglobulin concentrations were determined in 12 patients with solitary cold nodule or multinodular goitre. Of the 12 patients studied, seven had significant (P less than 0.05) elevations of serum thyroglobulin after aspiration. It is suggested that circulating thyroglobulin may increase after minor trauma to thyroid tissue such as following fine needle aspiration.
为了证明细针穿刺活检是否会导致甲状腺球蛋白释放进入循环系统，以及在穿刺过程中组织学诊断与甲状腺球蛋白从甲状腺释放之间是否存在相关性，我们对12例患有孤立性冷结节或结节性甲状腺肿的患者测定了血清甲状腺球蛋白浓度。在研究的12例患者中，7例在穿刺后血清甲状腺球蛋白有显著升高（P<0.05）。提示甲状腺组织受到轻微创伤（如细针穿刺后）后，循环中的甲状腺球蛋白可能会增加。
