Division of Pediatric Hematology and Oncology -Department of Hematology, Spirito Santo Hospital, Via Fonte Romana, Pescara, Italy,
Curr Infect Dis Rep. 2013 Jun;15(3):278-87. doi: 10.1007/s11908-013-0337-1.
Invasive fungal infections are an important cause of morbidity and mortality in immunocompromised children. Increases in the incidence of systemic mycoses have been observed during the last 2 decades. Treatment of invasive fungal infections has improved through a better knowledge and application of current treatment strategies and through the development of new antifungal compounds. The purpose of this review is to provide antifungal treatment recommendations for pediatric patients that can help clinicians find the most suitable treatment for each specific case.
侵袭性真菌感染是免疫功能低下儿童发病和死亡的重要原因。在过去的 20 年中,全身性真菌病的发病率有所增加。通过更好地了解和应用当前的治疗策略以及开发新的抗真菌药物,侵袭性真菌感染的治疗得到了改善。本文旨在为儿科患者提供抗真菌治疗建议,以帮助临床医生为每个具体病例找到最合适的治疗方案。